Geographical authenticity evaluation of Mentha haplocalyx by LIBS coupled with multivariate analyzes  

作　　者：Xiaona LIU Xiaoqing CHE Kunyu LI Xibo WANG Zhaozhou LIN Zhisheng WU Qiusheng ZHENG 刘晓娜;车晓青;李坤玉;王喜波;林兆洲;吴志生;郑秋生(College of Integrated Traditional Chinese Medicine and Western Medicine,Binzhou Medical University,Yantai 256603,People's Republic of China;Shandong Runzhong Pharmaceutical Co.,Ltd,Yantai 256603,People's Republic of China;Hebei Baicaokangshen Pharmaceutical Co.,Ltd,Shenzhou 053800,People's Republic of China;Penglai Municipal Bureau of Ocean Development and Fishery,Penglai 265600,People's Republic of China;Beijing Institute of Clinical Pharmacy,Beijing 100035,People’s Republic of China;Beijing University of Chinese Medicine,Beijing 100102,People's Republic of China)

机构地区：[1]College of Integrated Traditional Chinese Medicine and Western Medicine,Binzhou Medical University,Yantai 256603,People's Republic of China [2]Shandong Runzhong Pharmaceutical Co.,Ltd,Yantai 256603,People's Republic of China [3]Hebei Baicaokangshen Pharmaceutical Co.,Ltd,Shenzhou 053800,People's Republic of China [4]Penglai Municipal Bureau of Ocean Development and Fishery,Penglai 265600,People's Republic of China [5]Beijing Institute of Clinical Pharmacy,Beijing 100035,People’s Republic of China [6]Beijing University of Chinese Medicine,Beijing 100102,People's Republic of China

出　　处：《Plasma Science and Technology》2020年第7期44-50,共7页等离子体科学和技术（英文版）

基　　金：supported by National Natural Science Foundation of China(Nos.81903796,81603396 and 31870338);the National Key Research and Development Program of China(No.2019YFC1711200);Major new drug innovation project of the ministry of science and technology(2018ZX09201011);Scientific and Technological Planning Projects of Colleges and Universities of Shandong Province(No.J18KA287);Binzhou Medical University Research Startup Fund Project(No.BY2016KYQD02)。

摘　　要：Mentha haplocalyx(mint)is a significant traditional Chinese medicine(TCM)listed in the Catalogue of’Medicinal and Food Homology’,therefore,its geographical origins(GOs)are critical to the medicinal and food value.Laser-induced breakdown spectroscopy(LIBS)is an advanced analytical technique for GOs certification,due to the fast multi-elemental analysis requiring minimal sample pretreatment.In this study,LIBS data of sampled mint from five GOs were investigated by LIBS coupled with multivariate statistical analyzes.The spectral data was analyzed by two chemometric algorithms,i.e.principal component analysis(PCA)and least squares support vector machines(LS-SVM).Specifically,the performance of LS-SVM with least kernel and radial basis function(RBF)kernel was explored in sensitivity and robustness tests.Both LS-SVM algorithms exhibited excellent performance of classification in sensitive test and good performance(a little inferior)in robustness test.Generally,LS-SVM with linear kernel equally outperformed LS-SVM based on RBF kernel.The result indicated the potential for future applications in herbs and food,especially for in situ GOs applications of TCM authenticity rapidly.

关 键 词：laser-induced breakdown spectroscopy Mentha haplocalyx geographical origin least squares support vector machines herb authenticity 

分 类 号：R284.1[医药卫生—中药学]