血脂异常心血管疾病患者给予他汀类联合心血管药物治疗的效果分析  

Analysis of the Effect of Statins combined with Cardiovascular Drugs in Patients with Dyslipidemia

作　　者：任寰 苏嘉华 金鑫 杜鹤 REN Huan;SU Jia-hua;JIN Xin;DU He(Department of Internal Medicine(Cardiovascular),Zhongshan Second People's Hospital,Zhongshan 528400,China;South District Branch,Zhongshan Second People's Hospital,Zhongshan 528400,China)

机构地区：[1]中山市第二人民医院内科(心血管),广东中山528400 [2]中山市第二人民医院南区分院,广东中山528400

出　　处：《中国医药指南》2020年第20期93-94,共2页Guide of China Medicine

摘　　要：目的本次实验将对监所在押人员血脂异常的心血管疾病采用他汀类药物治疗依从性的相关因素进行探讨,提出改善策略。方法实验选取了2017年12月至2019年12月中山市第二人民医院南区分院住院部及中山市看守所门诊部就诊的监所在押患者,选用他汀类药物治疗血脂异常的心血管疾病。对照组患者阿司匹林肠溶片进行治疗,观察组患者则阿司匹林肠溶片+阿托伐他汀,对照组和观察组均在原心血管疾病药物治疗不变基础上加用实验用药物,在治疗两个月后观察应用效果。结果从治疗疗效上看,观察组患者的总疗效率为95.0%(57/60),对照组则为88.3%(53/60),差异具有统计学意义。与此同时,我们对比了患者的总胆固醇、三酰甘油、低密度脂蛋白胆固醇和高密度脂蛋白胆固醇含量,其观察组分别为(4.03±0.13)mmol/L、(1.22±0.15)mmol/L、(3.00±0.85)mmol/L和(2.86±0.11)mmol/L,对照组则为(4.98±0.66)mmol/L、(1.88±0.35)mmol/L、(3.46±1.28)mmol/L和(3.66±1.38)mmol/L,差异具有统计学意义。此外,观察组的医患关系满意度为93.3%(56/60),明显高于对照组医患关系满意度83.3%(50/60),差异具有统计学意义。结论他汀类药物治疗心血管疾病依从性的影响因素非常多,包括患者病程以及健康知识、他汀类药物知识、用药时间长短、医患关系等方面。此外,使用他汀类药物能够改善患者的临床病症,提升临床心血管数据指标,具有临床推广价值。Objective This experiment will explore the factors related to the compliance of statins in the treatment of cardiovascular diseases with dyslipidemia,and put forward the improvement strategies.Methods From December 2017 to December 2019,the inpatients of South District branch of Zhongshan Second People’s Hospital and the outpatients of Zhongshan detention center were selected to treat the cardiovascular diseases with dyslipidemia with statins.The control group was treated with aspirin enteric coated tablets,while the observation group was treated with aspirin enteric coated tablets+atorvastatin.Both the control group and the observation group were treated with experimental drugs on the basis of the original cardiovascular disease drug treatment unchanged,and the application effect was observed two months later.Results In terms of therapeutic effect,the total therapeutic efficiency of the observation group was 95.0%(57/60),while that of the control group was 88.3%(53/60).At the same time,we compared the total cholesterol,triglyceride,low-density lipoprotein cholesterol and high-density lipoprotein cholesterol of the patients in the observation group,which were(4.03±0.13)mmol/L,(1.22±0.15)mmol/L,(3.00±0.85)mmol/L and(2.86±0.11)mmol/L respectively,and(4.98±0.66)mmol/L,(1.88±0.35)mmol/L,(3.46±1.28)mmol/L and(The difference was statistically significant(3.66±1.38)mmol/L.In addition,the satisfaction rate of the observation group was 93.3%(56/60),which was significantly higher than that of the control group(83.3%).Conclusion There are many factors influencing the compliance of statins in the treatment of cardiovascular diseases,including the course of disease,health knowledge,knowledge of statins,duration of medication,doctor-patient relationship and so on In addition,the use of statins can improve the clinical symptoms of patients,improve the clinical cardiovascular data indicators,with clinical promotion value.

关 键 词：他汀类药物 血脂异常 心血管疾病 依从性 医患关系 

分 类 号：R54[医药卫生—心血管疾病]