连续喂养方案对早产婴儿生长发育的影响  

Effects of continuous feeding on the growth and development of premature infants

作　　者：张庆庆[1] 孙宇 李玲[1] 任燕[2] 马田君[3] Zhang Qingqing;Sun Yu;Li Ling;Ren Yan;Ma Tianjun(Department of Critical Care Medicine,Xinjiang Uygur Autonomous Region People′s Hospital,Urumqi 830001,China;Neonatal Department,Xinjiang Uygur Autonomous Region People′s Hospital,Urumqi 830001,China;Department of Obstetrics and Gynecology,Heze City Hospital Daobei Hospital,Heze,274000,China)

机构地区：[1]新疆维吾尔自治区人民医院重症医学科,乌鲁木齐830001 [2]新疆维吾尔自治区人民医院新生儿科,乌鲁木齐830001 [3]山东省菏泽市立医院道碑街院区妇产科,274031

出　　处：《中国实用护理杂志》2020年第21期1634-1638,共5页Chinese Journal of Practical Nursing

摘　　要：目的:探究早产儿实施连续喂养方法对生长发育的影响。方法:选择新疆维吾尔自治区人民医院82例早产儿作为研究对象,其出生时间均在2018年3月至2019年3月,依据喂养方式不同将其分为对照组及观察组,每组各41例。对照组早产儿实施间歇喂养方法,观察组早产儿实施连续喂养方法。比较2组黄疸消退时间以及住院时间;喂养前、喂养6个月后2组早产儿血清生长激素和胰岛素样生长因子-1水平;喂养6个月后2组早产儿智力发育指数(MDI)以及运动发育指数(PDI);体质量、头围以及身高情况;不良反应情况。结果:观察组早产儿黄疸消退时间为(8.01±1.52) d,住院时间(28.41±3.57) d,均短于对照组的(10.28±2.29)、(36.19±6.47) d,差异具有统计学意义( t值为5.288、6.741, P<0.01)。对照组与观察组早产儿喂养前在血清生长激素和胰岛素样生长因子-1水平方面比较差异无统计学意义( t值为0.160、0.075, P>0.05);喂养6个月后观察组早产儿在血清生长激素和胰岛素样生长因子-1水平均高于对照组( t值为6.895、19.537, P<0.01)。喂养6个月后观察组早产儿MDI指数是115.26±7.93、PDI指数是107.64±8.66,均高于对照组的96.17±13.57、94.52±10.89( t值为7.777、6.038, P<0.01)。观察组早产儿喂养6个月后体质量、头围以及身高增长水平均高于对照组( t值为7.590、10.124、15.661, P<0.05)。观察组早产儿在院内感染、多次呼吸暂停、胃潴留、新生儿坏死性小肠结肠炎方面不良反应率均低于对照组( χ2值为5.399~21.006, P<0.05)。 结论:对早产儿实施连续喂养方法可显著提升其机体生长激素和胰岛素样生长因子-1水平,有利于其机体生长发育,同时还可减少不良反应的发生,缩短早产儿住院时间,具有一定的临床应用价值。Objective To explore the effect of continuous feeding on the growth and development of premature infants.Methods A total of 82 cases of premature infants in our hospital were selected as the research objects,whose birth time was from March 2018 to March 2019.According to different feeding methods,they were divided into control group and observation group,41 cases in each group.The control group was fed intermittently and the observation group was fed continuously.Before and after 6 months of feeding,the levels of serum growth hormone and insulin-like growth factor-1,the mental development index(MDI)and physical development index(PDI),body mass,head circumference and height,and adverse reactions were compared.Results The time of jaundice regression and hospitalization time in the observation group were(8.01±1.52)d,(28.41±3.57)d,shorter than(10.28±2.29)d,(36.19±6.47)d in the control group,the difference was statistically significant(t value was 5.288,6.741,P<0.05).There was no significant difference between the control group and the observation group in the levels of serum growth hormone and insulin-like growth factor-1 before feeding(t value was 0.160,0.075,P>0.05).After feeding for 6 months,the levels of serum growth hormone and insulin-like growth factor-1 in the experimental group were higher than those in the control group(t value was 6.895,19.537,P<0.05).Six months after feeding,the MDI and PDI of the observation group were 115.2±67.93 and 107.6±48.66 respectively,higher than 96.17±13.57,94.52±10.89 in the control group(t value was 7.777,6.038,P<0.05).After feeding for 6 months,the growth level of body weight,head circumference and height in the observation group was higher than that in the control group(t value was 7.590,10.124,15.661,P<0.05).The adverse reactions of premature infants in hospital infection,multiple apnea,gastric retention and neonatal necrotizing enterocolitis were lower than those in the control group(χ2 value was 5.399-21.006,P<0.05).Conclusions Continuous feeding can significantl

关 键 词：生长发育 生长激素 胰岛素样生长因子-1 间歇喂养 连续喂养 早产儿 

分 类 号：R174.4[医药卫生—妇幼卫生保健]