Efficacy of Acupuncture Combined with Local Anesthesia in Ischemic Stroke Patients with Carotid Artery Stenting:A Prospective Randomized Trial  

作　　者：XIONG Wei ZHAO Chun-mei AN Li-xin XIE Si-ning JIA Chun-rong 

机构地区：[1]Department of Anesthesiology,Beijing Tiantan Hospital,Capital Medical University,Beijing 100015,China [2]Department of Anesthesiology,Beijing Friendship Hospital,Capital Medical University,Beijing 100050,China [3]Department of Traditional Chinese Medicine,Beijing Tiantan Hospital,Capital Medical University,Beijing 100015,China

出　　处：《Chinese Journal of Integrative Medicine》2020年第8期609-616,共8页中国结合医学杂志（英文版）

基　　金：Supported by the Beijing Chinese Medicine Science and Technology Development Fund(No.JJ2014-04)。

摘　　要：Objective:To evaluate the efficacy of electro-acupuncture(EA)or transcutaneous electrical acupoint stimulation(TEAS)on perioperative cerebral blood flow(CBF)and neurological function in ischemic stroke(IS)patients undergoing carotid artery stenting(CAS).Methods:In total,124 consecutive IS patients were randomly allocated to the EA,TEAS,and sham groups(groups A,T,and S;41,42,and 41 cases,respectively)by softwarederived random-number sequence.Groups A and T received EA and TEAS,respectively,at the Shuigou(GV 26)and Baihui(GV 20),Hegu(LI4)and Waiguan(TE 5)acupoints.Group S received sham EA.The stimulation was started from 30 min before surgery until the end of the operation.The primary outcome was the CBF at 30 min after surgery,which was measured by transcranial Doppler sonography.The secondary outcomes included hyperperfusion incidence and neurological function.National Institutes of Health Stroke Scale(NIHSS)and General Evaluation Scale(GES)scores were recorded at 1 week,1 month,and 3 months postoperatively.Results:Mean CBF velocity at 30 min after surgery in groups A and T was much lower than that in Group S(P<0.05);the incidence of hyperperfusion in Groups A and T was also lower than that in group S(P<0.05).Acupuncture was an independent factor associated with reduced incidence of hyperperfusion(OR=0.042;95%CI:0.002–0.785;P=0.034).NIHSS and GES scores improved significantly at 1 week postoperatively in Groups A and T than in Group S(P<0.05).Relative to Group S,groups A and T exhibited significantly lower incidences of moderate pain,as well as higher incidences of satisfaction with anesthesia,at 1 day postoperatively(P<0.05).Conclusion:EA or TEAS administered in combination with local anesthesia during CAS can inhibit transient increases in CBF,reduce the incidence of postoperative hyperperfusion,and improve neurological function.

关 键 词：ELECTRO-ACUPUNCTURE transcutaneous electrical acupoint stimulation carotid artery stenting cerebral blood flow neurological function 

分 类 号：R246.2[医药卫生—针灸推拿学]