基于数据挖掘的当代医家治疗儿童咳嗽变异性哮喘风邪犯肺证用药规律探析  

Analysis of Medication Regularity for Modern Doctors Treating Cough Variant Asthma in Children with Wind Pathogen Invading Fei Syndrome Based on Data Mining

作　　者：司振阳[1] 张骠[1] SI Zhen-yang;ZHANG Biao(Department of Pediatric,Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine,Nanjing 210022)

机构地区：[1]南京中医药大学附属南京中医院儿科,南京210022

出　　处：《中国中西医结合杂志》2020年第7期801-804,共4页Chinese Journal of Integrated Traditional and Western Medicine

基　　金：江苏省中医药管理局资助项目(No.LZ13100);南京市医学科技发展资金资助(No.QRX17188)。

摘　　要：目的基于现代文献探析当代医家治疗儿童咳嗽变异性哮喘风邪犯肺证的用药特点和组方规律。方法以"咳嗽变异性哮喘""中医"为主题词,检索1997年1月—2017年4月中国期刊全文数据库、维普中文科技期刊全文数据库、万方数据库中当代医家治疗儿童咳嗽变异性哮喘风邪犯肺证的处方。通过Excel 2010建立药物数据库,然后应用SPSS 16.0、WEKA 3.9以及PAJEK 3.1等软件挖掘处方中的用药特点和组方规律。结果研究最终纳入文献55篇,涉及中药处方55首,中药112味,药物总频数575次,使用频率≥10%的药物30味。处方中的核心配伍药物包括麻黄、地龙、甘草、蝉蜕、苦杏仁、黄芩、桔梗、百部和僵蚕等。结论宣降肺气、止咳平喘是当代医家治疗儿童咳嗽变异性哮喘风邪犯肺证的核心用药治法。Objective To analyze medication characteristics and prescription regularity of modern doctors treating cough variant asthma in children with wind pathogen invading Fei syndrome based on modern literature.Methods Prescriptions of modern doctors for treating cough variant asthma in children with wind pathogen invading Fei in China National Knowledge Infrastructure,Chinese Scientific Journals Database,and Wanfang Data were retrieved.The time limit for retrieval was from January 1997 to April 2017.A drug database was established by Excel 2010.Then the medication features and the regularity of prescriptions were mined by means of SPSS 16.0,WEKA 3.9 and PAJEK 3.1.Results Totally 55 prescriptions were screened,involving 112 kinds of Chinese herbs and 575 frequencies.The results showed 30 herbs with a high frequency(≥10%).The core compatible herbs in prescriptions covered Herba ephedrae,Pheretima,Radix glycyrrhizae,Periostracum cicadae,Semen armeniacae amarum,Radix scutellariae,Radix platycodonis,Radix stemonae and Bombyx batryticatus.Conclusion Ventilating Fei and relieving cough and dyspnea was the core medication rules for treating cough variant asthma in children with wind pathogen invading Fei.

关 键 词：咳嗽变异性哮喘 用药规律 数据挖掘 儿童 

分 类 号：R272[医药卫生—中医儿科学] R249[医药卫生—中医学]