儿童阑尾炎病原菌分布和耐药性分析  

Distribution and Drug Resistance of Pathogens in Children with Appendicitis

作　　者：陈虹宇[1] 张奕[1] 赖建威 孙丽芳[1] CHEN Hong-yu;ZHANG Yi;LAI Jian-wei;SUN Li-fang(Shenzhen Children’s Hospital,Shenzhen,Guangdong,518026)

机构地区：[1]广东省深圳市儿童医院检验科,518026

出　　处：《岭南急诊医学杂志》2020年第3期271-274,共4页Lingnan Journal of Emergency Medicine

摘　　要：目的:了解某院儿童阑尾炎手术中留取的阑尾脓病原菌分布和耐药性,以指导临床合理使用抗菌药物。方法:对该院阑尾炎患儿2014~2018年阑尾脓病原菌的耐药性及临床资料进行回顾统计分析。比较大肠埃希菌是否产超广谱β内酰胺酶(ESBL)的耐药性差异。结果:病原菌分离率居前四的依次是大肠埃希菌、铜绿假单胞菌、肺炎克雷伯菌、睾丸酮丛毛单胞菌,分别占73.25%、12.32%、4.67%、4.18%。统计学分析,药敏结果对大多数抗生素的耐药率较低。结论:儿童阑尾炎病原菌以革兰阴性菌为主,应根据本院检出菌的耐药谱进行药物选择。Objective:To understand the distribution and drug resistance of the pathogens of appendiceal pus in children′s appendicitis operation in a hospital,so as to guide the clinical rational use of antibiotics. Methods:The drug resistance and clinical data of appendiceal pyogenic bacteria in children with appendicitis from 2014 to 2018 were analyzed retrospectively. The differences of resistance between Escherichia coli producing extended spectrum β-lactamase(ESBL)were compared. Results:The top four pathogens were Escherichia coli,Pseudomonas aeruginosa,Klebsiella pneumoniae and Trichomonas testosterone,accounting for 73.25%,12.32%,4.67% and 4.18% respectively.Statistical analysis showed that the drug resistance rate of most antibiotics was low. Conclusion:Gram negative bacteria are the main pathogens of appendicitis in children. Drug selection should be based on the drug resistance spectrum of the bacteria detected in our hospital.

关 键 词：儿童 阑尾炎 病原菌 耐药性 

分 类 号：R446.5[医药卫生—诊断学] R725.7[医药卫生—临床医学]