门急诊呼吸道感染抗菌药物不合理用药分析  

Analysis of the Irrational Use of Antibacterial Drugs Against Respiratory Infections in Emergency and Outpatient

作　　者：刘立丽[1] LIU Lili(Beijing Changping District Hospital of Integrated Traditional Chinese and Western Medicine,Beijing 102208,China)

机构地区：[1]北京市昌平区中西医结合医院,北京102208

出　　处：《中国药物警戒》2020年第8期513-517,共5页Chinese Journal of Pharmacovigilance

摘　　要：目的为促进呼吸道感染抗菌药物合理使用提供参考。方法收集我院2018年7月至2019年12月门急诊25%医生呼吸道感染抗菌药物不合理处方。根据不合理处方构成因素,用Excel 2017分类统计不合理用药构成比,进行帕累托图分析主要因素和次要因素。结果抗菌药物处方共7 937张,其中不合理处方226张,占2.85%。年龄分布以20~60岁为主,主要科室集中在发热急诊、心内科、呼吸科、老年科、儿科、急诊、内分泌科。适应证不适宜和用法用量不适宜构成比为80.09%,是不合理用药的主要因素;遴选药品不适宜构成比为89.18%,是不合理用药的次要因素。结论抗菌药物的使用存在较多问题,应根据不合理处方主要科室、年龄,采取有针对性的处方审核,对出现频次较高的问题发布用药安全警示,持续优化治疗方案,确保门急诊抗菌药物的合理使用。Objective To provide a reference for promoting the rational use of antibacterial drugs against respiratory infections. Methods The paper collected 25% of irrational prescriptions of antibacterial drugs for respiratory infections by outpatient and emergency physicians from July, 2018 to December, 2019. According to the constituent of irrational prescriptions, the classification and statistical analysis on the constituents of irrational drugs use was made by Excel 2017, showing the major and minor factors by Pareto chart. Results Among 7,937 antibacterial prescriptions in total, 226 were irrational, accounting for 2.85%. The age distribution of irrational prescriptions is mainly between 20 and 60 years old, mainly from emergency department of fever, cardiology, respiratory department, geriatrics, pediatrics, emergency department and endocrinology department. Inappropriate indications and dosages was the major factor of irrational prescriptions, constituting for 80.09%.while the unsuitable drug selection was the minor factor, constituting for 89.18%. Conclusion There are many problems in the use of antibacterial drugs. According to the main departments and age distribution of irrational prescriptions, targeted prescription reviews should be adopted. Moreover, drugs safety warnings should be issued for problems that occurred frequently, and the treatment plan should be continuously optimized, in order to ensure the rational use of antibacterial drugs in emergency and outpatient departments.

关 键 词：呼吸道感染 抗菌药物 分析 不合理用药 

分 类 号：R969.3[医药卫生—药理学]