复方黄柏液尿道灌注联合多西环素口服治疗非淋菌性尿道炎的临床效果  

The clinical effect of urinary perfusion with compound phellodendron and oral doxycycline hydrochloride in the treatment of non-gonococcal urethritis

作　　者：陈靓 彭光玲 CHEN Liang;PENG Guangling(Department of Dermatology,the Fifth People′s Hospital of Chongqing,Chongqing 400062,China)

机构地区：[1]重庆市第五人民医院皮肤科,重庆400062

出　　处：《检验医学与临床》2020年第15期2189-2191,共3页Laboratory Medicine and Clinic

摘　　要：目的探讨采用复方黄柏液尿道灌注联合盐酸多西环素口服治疗非淋菌性尿道炎患者的临床疗效。方法选取2018年1月至2019年5月在该院就诊的120例非淋菌性尿道炎男性患者为研究对象,随机分为治疗组与对照组,每组60例。治疗组采用复方黄柏液尿道灌注联合盐酸多西环素口服;对照组仅口服盐酸多西环素。观察2组患者的临床疗效、不良反应及复发情况。结果治疗组患者的治疗有效率为93.33%,显著高于对照组(78.33%),差异有统计学意义(P<0.05)。治疗组与对照组患者均出现了轻微不良反应,但未终止用药,治疗结束后症状均自行消退。治疗组患者的复发率(6.67%)显著低于对照组(25.00%),差异有统计学意义(P<0.05)。结论在口服盐酸多西环素的同时联合采用复方黄柏液尿道灌注,可以显著提高非淋菌性尿道炎患者的临床疗效。Objective To explore the clinical effect of urinary perfusion with compound phellodendron and oral doxycycline hydrochloride in the treatment of non-gonococcal urethritis.Methods From January 2018 to May 2019,120 male patients with non-gonococcal urethritis were treated in the hospital as the study object,randomly divided into treatment group and control group,60 cases in each group.The treatment group was treated with urinary perfusion with compound phellodendron and doxycycline hydrochloride orally,while the control group was only treated with doxycycline hydrochloride orally.The clinical efficacy,adverse reactions and recurrence of the two groups were observed.Results The effective rate of the treatment group was 93.33%,which was significantly higher than that of the control group(78.33%),the difference was statistically significant(P<0.05).The treatment group and the control group had slight adverse reactions,but the medication was not terminated,and the symptoms subsided after the treatment.The recurrence rate in the treatment group(6.67%)was significantly lower than that in the control group(25.00%),the difference was statistically significant(P<0.05).Conclusion The combination of oral doxycycline hydrochloride and urinary perfusion with compound phellodendron can significantly improve the clinical efficacy of patients with non-gonococcal urethritis.

关 键 词：非淋菌性尿道炎 尿道灌注 复方黄柏液 盐酸多西环素 

分 类 号：R978.1[医药卫生—药品] R695[医药卫生—药学]