Pillar[5]arene-based [3]rotaxanes: Convenient construction via multicomponent reaction and pH responsive self-assembly in water  

作　　者：Junmei Ye Runmiao Zhan Wenjuan Yang Ying Han Hao Guo Ju Xie Chaoguo Yan Yong Yao 

机构地区：[1]School of Chemistry and Chemical Engineering,Yangzhou University,Yangzhou 213300,China [2]School of Chemistry and Chemical Engineering,Nantong University,Nantong 226019,China

出　　处：《Chinese Chemical Letters》2020年第6期1550-1553,共4页中国化学快报（英文版）

基　　金：supported by the National Natural Science Foundation of China(Nos.21871227,21801139);Natural Science Foundation of Jiangsu Province(No.BK20180942);Natural Science Foundation of Nantong University for High-Level Talent(No.03083004)。

摘　　要：Four pillar[5]arene based[3]rotaxanes(1-4)involving two 1,4-diethoxypillar[5]arene(DEP5)rings and a dumbbell-shaped component were successfully synthesized.The dumbbell-shape molecules contain one longer bridge,two triazole sites and two multicomponent stoppers.After threading DEP5 rings with linear guests(G1-G4)which contain two benzaldehyde units,the base catalyzed three-component reaction of dimedone,malononitrile and benzaldehyde was performed to construct the stoppers and connected the pseudorotaxanes with stoppers to generate 1-4.The structures of[3]rotaxanes and their self-assembly behaviors were characterized by 1 H NMR,13C NMR,NOESY,HR-ESI-MS,DLS and TEM technologies.We hope that pillar[5]arene based[3]rotaxanes may have potential applications in drug delivery systems and molecular devices.

关 键 词：arene Rotaxane Multicomponent reaction Molecular machine SELF-ASSEMBLY 

分 类 号：O641.3[理学—物理化学]