叶酸受体介导的宫颈特殊染色法联合TCT检查和HPV检测法对宫颈病变的诊断价值  

The diagnostic value of folate receptor mediated cervical special staining combined with TCT and HPV detection in cervical lesions

作　　者：苏丽莉[1] 陈默[2] SU Lili;CHEN Mo(Health Management Center,the Fifth Affiliated Hospital of Sun Yat-sen University,Zhuhai,Guangdong 519000,China;Department of ENT&HN Surgery,the Fifth Affiliated Hospital of Sun Yat-sen University,Zhuhai,Guangdong 519000,China)

机构地区：[1]中山大学附属第五医院健康管理中心,广东珠海519000 [2]中山大学附属第五医院耳鼻咽喉头颈外科,广东珠海519000

出　　处：《国际检验医学杂志》2020年第15期1853-1856,共4页International Journal of Laboratory Medicine

摘　　要：目的研究叶酸受体介导的宫颈特殊染色法(FRD)、液基薄层细胞学(TCT)检查和人乳头瘤病毒(HPV)检测法在宫颈病变人群鉴别中的意义。方法以该院2016年3月至2019年10月收治的120例宫颈癌患者作为观察组,另选取同期该院120例体检健康者作为对照组。分别对两组研究对象开展FRD、TCT检查和HPV检测法,分析两组研究对象FRD、TCT检查和HPV检测法阳性结果差异,分析FRD、TCT检查和HPV检测法联合检测的诊断效能。结果观察组FRD、TCT检查和HPV检测法阳性明显高于对照组,联合检测的诊断灵敏度明显优于单项检测。结论FRD、TCT检查和HPV检测法在宫颈病变的诊断中灵敏度较高,诊断时间明显缩短,值得临床推广应用。Objective To study the significance of flolate receptor mediated cervical special staining(FRD),liquid based thin layer cytology(TCT)and human papillomavirus(HPV)in the identification of cervical lesions.Methods A total of 120 patients with cervical cancer admitted to the hospital from March 2016 to October 2019 were selected as the observation group,and another 120 healthy persons undergoing physical examination in the hospital at the same time were selected as the control group.The FRD,TCT and HPV detections in the two groups were examined respectively,and the differences of the positive rates of FRD,TCT and HPV in the two groups were analyzed.The dignostic efficacy of combined detection of FRD,TCT and HPV was analyzed.Results The positive rates of FRD,TCT and HPV in the observation group were significantly higher than those in the control group.The sensitivity of the combined detection was significantly better than that of the single detection.Conclusion The sensitivity of FRD,TCT and HPV methods was relatively high,and the diagnosis time of patients is significantly shortened.It is suggested that they can be popularized clinically.

关 键 词：宫颈癌 叶酸受体介导的宫颈特殊染色法 液基薄层细胞学检查 人乳头瘤病毒 

分 类 号：R711.3[医药卫生—妇产科学]