人类免疫缺陷病毒/获得性免疫缺陷综合征相关性眼病的研究进展  

Research progress of human immunodeficiency virus/acquired immunodeficiency syndrome related ophthalmopathy

作　　者：吴苑妮 张健[1] 宋心成 张瑞 王晓贞[3] 李鑫[1,2] Wu Yuanni;Zhang Jian;Song Xincheng;Zhang Rui;Wang Xiaozhen;Li Xin(Department of Center of Integrated Traditional Chinese and Western Medicine,Peking University Ditan Teaching Hospital,Beijing 100015,China;Department of Center of Integrated Traditional Chinese and Western Medicine,Beijing Ditan Hospital,Capital Medical University,Beijing 100015,China;Department of Ophthalmologic Center,Beijing Tongren Hospital,Capital Medical University,Beijing 100730,China)

机构地区：[1]北京大学地坛医院教学医院中西医结合中心,北京100015 [2]首都医科大学附属北京地坛医院中西医结合中心,北京100015 [3]首都医科大学附属北京同仁医院眼科中心,北京100730

出　　处：《中华实验和临床感染病杂志（电子版）》2020年第2期93-98,共6页Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition)

基　　金：十三五国家科技重大专项(No.2017ZX10205501-001-002)。

摘　　要：获得性免疫缺陷综合征(AIDS)是由人类免疫缺陷病毒(HIV)引起的、具有高病死率、高传播率的后天获得性免疫缺陷疾病。HIV主要侵犯人体免疫系统,靶向攻击CD4+T淋巴细胞,使其数量进行性减少(<200个/μl或低于总淋巴细胞的14%),易引发机会性感染和恶性肿瘤。近年来,随着社会的发展和人们观念意识的变化,HIV/AIDS患者病例数逐渐增多,相应的HIV/AIDS相关性眼部并发症的发生率亦逐渐增高。与一般眼部疾病相比,HIV/AIDS相关性眼病的临床表现特殊,治疗困难。本文对HIV/AIDS几种常见眼部疾病展开综述,对其最新研究进展进行总结,以期能够更加全面地了解此类疾病,及时准确地诊断病情以及合理地指导治疗,从而改善患者视力,减少痛苦,提高其生存质量。Acquired immunodeficiency syndrome(AIDS)is an acquired immunodeficiency disease caused by human immunodeficiency virus(HIV)infection,with high mortality and transmission rate.HIV mainly invades the human immune system,targetting CD4+T lymphocyte,making its number progressively reduced(<200/ml or<14%of total lymphocyte),and susceptible to opportunistic infections and malignant tumors.In recent years,with the development of society and the change of people’s concept and consciousness,the number of HIV/AIDS patients had gradually increased,and HIV/AIDS-related ocular complications had also gradually increased.Compared with general eye diseases,the clinical manifestations of AIDS-related ophthalmopathy are special and difficult to treat.This article reviewed several common eye diseases in HIV/AIDS and summarized the latest progress,in order to acquire more comprehensive understanding of these diseases,timely and accurate diagnosis and guiding treatment reasonably,to improve patients’vision,reduce the pain and improve the quality of patients’life.

关 键 词：获得性免疫缺陷综合征 人类免疫缺陷病毒 眼病 

分 类 号：R512.91[医药卫生—内科学] R711.3[医药卫生—临床医学]