B细胞在寄生细菌感染中除产生抗体以外的作用  

Functions of B cells in parasitic bacterial infections in addition to producing antibodies

作　　者：贾芳 周学章 Jia Fang;Zhou XueZhang(Key Laboratory of the Ministry of Education for the Conservation and Utilization of Special Biological Resources of Western China,Ningxia University,yinchuan,Ningxia,China 750021)

机构地区：[1]宁夏大学生命科学学院,西部特色生物资源保护与利用教育部重点实验室,宁夏银川750021

出　　处：《中国病原生物学杂志》2020年第6期733-736,共4页Journal of Pathogen Biology

基　　金：宁夏回族自治区重点研发计划项目(东西部合作)(No.2017BN04)。

摘　　要：传统认为B细胞主要通过产生抗体对免疫作出积极贡献,但是B细胞的另一个生物学特征与细菌寄生有关。除了抗体的产生,B细胞是先天免疫和适应性免疫的关键角色。在这篇综述中,我们重点讨论边缘区B细胞作为这些细菌感染的目标,并描述这些细菌感染如何影响和调节B细胞的发育和功能。Traditionally,B cells are thought to contribute to immunity mainly by producing antibodies,but B cells have other biological characteristics that are associated with parasitic bacteria in addition to producing antibodies.B cells play a key role in innate immunity and adaptive immunity.This review focuses on marginal zone B cells as targets of Salmonella,Brucella,Mycobacterium tuberculosis,Helicobacter pylori,and Listeria.How these bacteria affect and regulate the function and growth of B cells is described.

关 键 词：B细胞 细菌感染 寄生细菌 综述 

分 类 号：R378.911[医药卫生—病原生物学]