1303例高龄产妇妊娠结局的临床分析  

Clinical analysis of pregnancy outcome in 1303 cases of elderly women

作　　者：费晓萍 祝亚平 Fei Xiaoping;Zhu Yaping(Shanghai General Hospital of Nanjing Medical University,Shanghai 200080,China;Department of Obstetrics and Gynecology,the First People′s Hospital of Kunshan,Kunshan 215300,China)

机构地区：[1]南京医科大学附属上海一院临床医学院,上海200080 [2]江苏省昆山市第一人民医院妇产科,215300

出　　处：《中国医师杂志》2020年第7期1022-1025,1029,共5页Journal of Chinese Physician

基　　金：江苏大学2016年度医学临床科技发展基金(JLY20160055)。

摘　　要：目的 比较高龄产妇在妊娠合并症及并发症、围产儿结局及分娩方式等方面与适龄产妇的差异.方法 回顾性分析2016年12月至2017年2月在昆山市第一人民医院产科住院收治分娩的1 303例高龄产妇作为研究组,其中35 ~ 39岁的1 139例为研究组1,≥40岁的164例为研究组2,随机抽取同期分娩的年龄<35岁的产妇1 303例为对照组,分娩孕周均≥28周.分析3组产妇妊娠合并症及并发症、围产儿结局、分娩方式等的差异.结果 与对照组相比,研究组妊娠期高血压疾病、妊娠期糖尿病、妊娠合并甲状腺功能减退、前置胎盘、子宫肌瘤以及早产、胎儿窘迫、巨大儿及剖宫产率增高,差异有统计学意义(P<0.05);三组间妊娠期肝内胆汁淤积症、胎膜早破、产后出血、卵巢囊肿、低出生体重儿及死胎差异无统计学意义(P>0.05).结论 高龄产妇妊娠后母儿风险增加,剖宫产率高,提倡适龄生育并加强对高龄产妇的孕期监督和管理,以保障母婴安全.Objective To compare the differences of pregnancy complications,perinatal outcomes and mode of delivery between the elderly and the right-age mothers.Methods A retrospective analysis was conducted on 1303 elderly women who were hospitalized and delivered in the obstetrics department of the First People′s Hospital of Kunshan City from December 2016 to February 2017.Among them,1139 cases aged 35-39 years were selected as study group 1 and 164 cases≥40 years old as study group 2.The differences of pregnancy complications,perinatal outcomes and delivery modes among the three groups were analyzed.Results Compared with the control group,pregnancy-induced hypertension,gestational diabetes mellitus,hypothyroidism,placenta previa,uterine fibroids,premature delivery,fetal distress,macrosomia and cesarean section rates in the study group were significantly higher(P<0.05).There were no significant difference in intrahepatic cholestasis of pregnancy,premature rupture of membranes,postpartum hemorrhage,ovarian cyst,fetal growth restriction and stillbirth among the groups(P>0.05).Conclusions The risk of mother and child increases and the rate of cesarean section is high in older mothers.It is advocated to give birth at the right age and to strengthen the supervision and management of the gestation period of the elderly maternal so as to ensure the safety of mother and child.

关 键 词：妊娠结局 妊娠并发症 高龄妊娠 

分 类 号：R714.2[医药卫生—妇产科学]