贵阳市中老年女性人群睡眠行为与糖尿病患病的关联性分析  

Correlation Between Sleep Behaviors and Diabetes Prevalence among Middle-aged and Elderly Women in Guiyang

作　　者：王子云 杨敬源[1,2] 关菡 胡瑾[1,2] 汪俊华 刘海燕 杨婷婷[1,2] 蒋芝月 刘丽[1,2] 洪峰 WANG Ziyun;YANG Jingyuan;GUAN Han;HU Jin;WANG Junhua;LIU Haiyan;YANG Tingting;JIANG Zhiyue;LIU Li;HONG Feng(School of Public Health,Guizhou Medical University,Guiyang 550025,China;Key Laboratory of Environmental Pollution Monitoring and Disease Control,Ministry of Education,Guizhou Medical University,Guiyang 550025,China)

机构地区：[1]贵州医科大学公共卫生学院,贵州省贵阳市550025 [2]贵州医科大学环境污染与疾病监控教育部重点实验室,贵州省贵阳市550025

出　　处：《中国全科医学》2020年第29期3706-3711,共6页Chinese General Practice

基　　金：开展居民疾病谱调查工作项目(BCXZFCG2016-023A)。

摘　　要：背景女性进入更年期后,慢性病发病风险上升,而睡眠障碍是中老年女性常见的健康危险因素之一,也是近年糖尿病病因学研究的热点之一。目的调查贵阳市中老年(40岁及以上)女性人群睡眠特征及糖尿病现患情况,并分析二者的相关性。方法2017年6—10月,在贵阳市卫生和计划生育委员会的支持下,贵州医科大学公共卫生学院采用分层、多级抽样的方法选择贵阳市云岩区、乌当区、白云区、修文县四个区县进行入户调查,收集其年龄、受教育年限、婚姻状况、民族、吸烟状况、饮酒状况、运动频率、三餐规律饮食情况、生育史、绝经状况、高血压患病、体质量情况、中心性肥胖、午睡、午睡时间、夜间睡眠时间、夜间睡眠质量等情况,并比较糖尿病患者与非糖尿病人群之间的差异。采用多因素Logistic回归分析探讨糖尿病的相关因素。结果共纳入2758例40岁及以上中老年女性进行分析。其中,自我报告被诊断为糖尿病患者150例,自我报告患病率为5.4%。糖尿病患者年龄相对较大,且非在婚、汉族、运动频率≥1 d/周、三餐规律饮食、已绝经、高血压患病、超重或肥胖、中心性肥胖、午睡、夜间睡眠质量差所占比例高于非糖尿病人群(P<0.05)。多因素Logistic回归分析结果显示,高血压〔OR=3.626,95%CI(2.463,5.337),P<0.001〕、中心性肥胖〔OR=1.782,95%CI(1.111,2.858),P=0.017〕、午睡情况〔OR=1.727,95%CI(1.161,2.569),P=0.007〕、夜间睡眠质量差〔OR=1.682,95%CI(1.140,2.482),P=0.009〕是40岁以上中老年女性糖尿病患病的相关因素。非高血压患者午睡〔OR=1.888,95%CI(1.038,3.435),P=0.037〕、夜间睡眠质量差〔OR=1.993,95%CI(1.115,3.563),P=0.020〕与糖尿病患病相关,而中心性肥胖者的午睡情况〔OR=1.588,95%CI(1.033,2.442),P=0.035〕也与糖尿病患病相关。超重或肥胖与夜间睡眠质量差〔OR=1.759,95%CI(1.098,2.820),P=0.019〕、中心性Background The risk of chronic diseases in female population increases after menopause.Sleep disorders are common health risk factors for middle-aged and elderly women,and are also a hot research topic about the etiology of diabetes in recent years.Objective To evaluate the correlation between sleep characteristics and diabetes prevalence among middle-aged and elderly(≥40 years)women in Guiyang.Methods From June to October 2017,with the support of Guiyang Health and Family Planning Commission,a household survey was conducted by School of Public Health,Guizhou Medical University among four districts and counties(Yunyan,Wudang,Baiyun and Xiuwen)in Guiyang City selected with stratified multistage sampling.Information on age,years of education,marriage status,nationality,tobacco smoking prevalence,alcohol consumption prevalence,exercise frequency,eating pattern,reproductive history,menopause,hypertension prevalence,BMI,central obesity,prevalence and duration of daytime napping,sleep duration and sleep quality at night,and so on in participants was collected,and was compared between those with diabetes and those without.The multivariate logistic regression model was used to analyze and explore the related factors of diabetes.Results A total of 2758 cases were included for analysis,among whom 150(5.4%)had a self-reported diagnosis of diabetes.Those with diabetes had greater mean age,and higher proportions of being unmarried,Han nationality,exercise frequency≥1 d/week,regular eating pattern,menopause,hypertension,overweight or obesity,central obesity,daytime napping,poor sleep quality at night than those without(P<0.05).Multivariate Logistic regression analysis showed that hypertension〔OR=3.626,95%CI(2.463,5.337),P<0.001〕,central obesity〔OR=1.782,95%CI(1.111,2.858),P=0.017〕,daytime napping〔OR=1.727,95%CI(1.161,2.569),P=0.007〕and poor sleep quality at night〔OR=1.682,95%CI(1.140,2.482),P=0.009〕were factors associated with diabetes in women over 40 years old.Daytime napping behavior〔OR=1.888,95%CI(1.0

关 键 词：睡眠 糖尿病 肥胖 高血压 女性 中老年 

分 类 号：R163[医药卫生—公共卫生与预防医学] R587.1