CRP评估高脂血症性急性胰腺炎严重程度的意义  

The significance of CRP in evaluating the severity of hyperlipidemic acute pancreatitis

作　　者：李娇[1] 李莉[1] LI Jiao;LI Li(Department of General Surgery,Tianjin Haihe Hospital,Tianjin 300350,China)

机构地区：[1]天津市海河医院普外科,天津300350

出　　处：《中国城乡企业卫生》2020年第7期48-50,共3页Chinese Journal of Urban and Rural Enterprise Hygiene

摘　　要：目的评估C反应蛋白(CRP)在高脂血症性急性胰腺炎(HLAP)及非高脂血症性急性胰腺炎(NHLAP)严重程度中的意义。方法回顾性分析2014年1月-2019年12月天津市海河医院收治的急性胰腺炎(AP)患者140例,其中将HLAP患者60例作为HLAP组,NHLAP患者80例作为NHLAP组。分析比较两组临床资料以及CRP水平。结果两组平均年龄比较,差异有统计学意义(P<0.01);且HLAP组脂肪肝、糖尿病、高血压、AP复发率均高于NHLAP组,差异均有统计学意义(P<0.05)。HLAP及NHLAP两组在腹痛至入院间隔时间及腹痛持续时间上差异无统计学意义(P>0.05)。HLAP组血清CRP水平在第1、3、5天均明显高于NHLAP组,差异均有统计学意义(P<0.05)。MAP中,HLAP组患者血清CRP水平在第3天和第5天明显高于NHLAP组患者,差异均有统计学意义(P<0.05),而第1天两组比较,差异无统计学意义(P>0.05)。在MSAP、SAP中,HLAP组患者血清CRP水平在第1、3、5天均明显高于NHLAP组,差异均有统计学意义(P<0.05)。结论HLAP发病年龄较小,合并症多,且复发率高,HLAP组中与NHLAP组不同严重程度患者中CRP水平不同,因此CRP对HLAP病情严重程度进行评估非常有意义,值得临床推广应用。Objective To evaluate the significance of C-reactive protein(CRP)in the severity of hyperlipidemic acute pancreatitis(HLAP)and non hyperlipidemic acute pancreatitis(NHLAP).Methods From January 2014 to December 2019,140 patients with acute pancreatitis(AP)admitted to Tianjin Haihe Hospital were analyzed retrospectively.Among them,60 cases of patients with HLAP and 80 cases of patients with NHLAP were treated as HLAP group and NHLAP group respectively.The clinical data and CRP level of two groups were analyzed and compared.Results The average age of two groups was compared,the difference was statistically significant(P<0.01);the fatty liver,diabetes,hypertension and the recurrence rate of AP in HLAP group were higher than those in NHLAP group,and the differences were statistically significant(P<0.05).There were no significant differences in the interval from abdominal pain to admission and the duration of abdominal pain between the two groups(P>0.05).The levels of serum CRP in HLAP group were significantly higher than those in NHLAP group on the 1 st,3 rd and 5 th day,and the differences were statistically significant(P<0.05).There were no significant differences in the interval from abdominal pain to admission and the duration of abdominal pain between the two groups(P>0.05).In MAP,the serum CRP levels of HLAP group were significantly higher than those of NHLAP group on the 3 rd and 5 th day,the differences were statistically significant(P<0.05).While on the first day,the two groups were compared,the difference was not statistically significant(P>0.05).In MSAP and SAP,the serum CRP levels in HLAP group were significantly higher than those in NHLAP group on the 1 st,3 rd and 5 th day(P<0.05).Conclusion The incidence age of HLAP was young,there were many complications,and the recurrence rate was high.The level of CRP in patients with different severity in HLAP group and NHLAP group was different.Therefore,it was very meaningful to evaluate the severity of HLAP by CRP,which was worthy of clinical promotion and applic

关 键 词：高脂血症 胰腺炎 C反应蛋白 

分 类 号：R6[医药卫生—外科学]