低效价红细胞血型抗体对新疆地区肿瘤患者输血效果的影响  

Effect of Low-Efficiency Erythrocyte Antibodies in Tumor Patients with Blood Transfusion in Xinjiang

作　　者：赵刚[1] 郭凡[2] 李君[3] 李清[1] ZHAO Gang;GUO Fan;LI Jun(Department of Blood Transfusion,Affiliated Traditional Chinese Medicine Hospital of Xinjiang Medical University,Urumqi 830011)

机构地区：[1]新疆医科大学附属中医医院输血科,830011 [2]新疆医科大学附属肿瘤医院检验科 [3]开滦总医院输血科

出　　处：《临床输血与检验》2020年第4期383-386,共4页Journal of Clinical Transfusion and Laboratory Medicine

基　　金：新疆医科大学附属中医医院院级课题(No.ZYY201619)资助。

摘　　要：目的研究低效价红细胞血型抗体对新疆地区肿瘤患者输血效果的影响。方法回顾性分析本院肿瘤入院患者667例,依照输血疗效分为输血有效组和输血无效组,分析两组数据在不同因素影响下的输血疗效及低效价抗体之间的关系。结果本研究的有效输注率为81.86%,不良反应发生率为0.45%。无效输血与妊娠次数、民族等因素密切相关,差异有统计学意义(P<0.05)。低效价抗体检出率,与妊娠次数、既往输血史及民族等因素密切相关,差异有统计学意义(P<0.05)。和抗人球蛋白法相比,不同检测方法对低效价抗体检出率明显不同,差异有统计学意义(P<0.05)。结论本地区患者存在输血无效的现象,低效价抗体是影响输血疗效的因素之一,医疗机构应合理设置复检规则,加强低效价抗体的检出。Objective To study the effect of low-titre erythrocyte antibodies on tumor patients with blood transfusion in Xinjiang.Methods A retrospective analysis was performed on 667 cases of tumor patients in our hospital.According to the efficacy of blood transfusion,the patients were divided into effective group and ineffective group.The relationship between the transfusion efficacy and low titre antibody under the influence of different factors is analyzed.Results The effective infusion rate in this study is 81.86%and the incidence of adverse reactions is 0.45%.Invalid blood transfusion is closely related to pregnancy frequency,nationality and other factors,and the difference was statistically significant(P<0.05).The detection rate of low potency antibody is closely related to the number of pregnancies,previous blood transfusion history and national factors,and the difference was statistically significant(P<0.05).Compared with antihuman globulin method,the detection rate of low potency antibody is significantly different in various detection methods(P<0.05).Conclusion The inefficacy of transfusions exists in patients in this region,and the low potency antibody is one of the factors affecting the efficacy of blood transfusion.Medical institutions should reasonably set up re-examination rules to strengthen the detection of low-valency antibodies.

关 键 词：低效价抗体 新疆地区 输血效果 

分 类 号：R446.6[医药卫生—诊断学]