中医药对溃疡性结肠炎肠黏膜屏障调控作用的研究进展  

Research progress on regulation of intestinal mucosal barrier of patients with ulcerative colitis with traditional Chinese medicine

作　　者：陈继超 Ji-Chao Chen(Department of Gastroenterology,Affiliated First Hospital of Zhejiang Chinese Medical University,Hangzhou 310051,Zhejiang Province,China)

机构地区：[1]浙江中医药大学附属第一医院消化内科,浙江省杭州市310051

出　　处：《世界华人消化杂志》2020年第15期725-729,共5页World Chinese Journal of Digestology

摘　　要：溃疡性结肠炎(ulcerative colitis,UC)是一种慢性肠道炎症性疾病,肠黏膜屏障结构损伤和功能失衡是其发生发展的重要机制,现代研究证实许多中医药具有调节炎性细胞、促进免疫活性物质分泌和维护肠内微生物生态等作用,对于肠黏膜屏障的维护和修复具有重要意义.本文结合中外文献,对中药单药成分和复方对UC黏膜屏障的调控作用及其机理作一阐述.Ulcerative colitis(UC)is a chronic intestinal inflammatory disease.Intestinal mucosal barrier structure damage and functional imbalance are important mechanisms for its occurrence and development.Modern research has confirmed that many traditional Chinese medicines have the functions of regulating inflammatory cells,promoting the secretion of immunologically active substances,and maintaining the intestinal microbial ecology.They are of great significance for the maintenance and repair of the intestinal mucosal barrier.This article elaborates the regulatory effect and mechanisms of single compositions of Chinese materia medica and compound prescriptions on the mucosal barrier of patients with UC.

关 键 词：溃疡性结肠炎 肠黏膜屏障 中医药 文献综述 

分 类 号：R259[医药卫生—中西医结合]