一种改进PSI协议的基因数据隐私保护方案  

Genomic data privacy-preserving scheme based on the improved PSI protocol

作　　者：田美金 马建峰 刘志全 冯丙文[1] 魏凯敏 TIAN Meijin;MA Jianfeng;LIU Zhiquan;FENG Bingwen;WEI Kaimin(College of Information Science and Technology,Jinan University,Guangzhou 510632,China;School of Cyber Engineering,Xidian University,Xi’an 710071,China)

机构地区：[1]暨南大学信息科学技术学院,广东广州510632 [2]西安电子科技大学网络与信息安全学院,陕西西安710071

出　　处：《西安电子科技大学学报》2020年第4期94-101,共8页Journal of Xidian University

基　　金：国家自然科学基金(61802146,61972178,61802145);广东省重点领域研发计划项目(2019B010136003);广东省数据安全与隐私保护重点实验室(2017B03031004);广东省基础与应用基础研究基金(2019A1515011017);广东省自然科学基金(2019B010137005,2018A030313813,2018A03031387,2017A030313390,2017A030313334);广州市科技计划(201804010428,201802010061);中央高校基本科研业务费专项资金(11618332,11617343);信息安全国家重点实验室开放课题;广东省信息安全技术重点实验室开放基金(2017B030314131);广东省智能信息处理重点实验室/深圳市媒体信息内容安全重点实验室开放基金。

摘　　要：为解决基因数据共享面临的隐私泄露问题,提出一种改进隐私集合交集计算协议的基因数据隐私保护方案。该方案采用布隆过滤器、布谷鸟哈希和随机不经意传输扩展协议,在用户进行致病基因检测时保护其基因组序列信息,并判断被检测者是否含有某种疾病因子。此外,在半诚实安全模型下,证明所提方案在致病基因检测场景中的正确性和安全性,并通过一系列实验验证所提方案的高效性。实验结果表明,所提方案的运行时间和通信开销明显低于现有的隐私集合交集计算方案。In order to solve the problem of privacy leakage in the sharing of genomic data,a genomic data privacy-preserving scheme based on the improved Private Set Intersection(PSI)computing protocol is presented,which leverages the Bloom Filter,Cuckoo Hash,and Random Oblivious Transfer(ROT)extension protocol to not only protect the genomic sequence information on the user when detecting a disease-causing gene but also judge whether he or she has some disease factors or not.Moreover,the correctness and security of the proposed scheme in the detection scenario of disease-causing genes are proved in the semi-honest security model.In addition,a series of experiments is conducted to verify the efficiency of the proposed scheme.The results reveal that the running time and communication overhead of the proposed scheme are much less than those of the existing PSI schemes.

关 键 词：隐私集合交集 不经意传输 基因隐私 隐私保护 

分 类 号：TP301.5[自动化与计算机技术—计算机系统结构]