来源于真菌AA9家族裂解性多糖单加氧酶的研究进展  

Research progress in fungal lytic polysaccharide monooxygenases from AA9 family

作　　者：郭宵 安亚静 柴成程 蒋露莹 路福平[1] 刘夫锋 戴玉杰[1] GUO Xiao;AN Ya-Jing;CHAI Cheng-Cheng;JIANG Lu-Ying;LU Fu-Ping;LIU Fu-Feng;DAI Yu-Jie(Key Laboratory of Industrial Fermentation Microbiology,Ministry of Education,Tianjin Key Laboratory of Industrial Microbiology,National Engineering Laboratory for Industrial Enzymes,College of Biotechnology,Tianjin University of Science&Technology,Tianjin 300457,China)

机构地区：[1]工业发酵微生物教育部重点实验室,天津市工业微生物重点实验室,工业酶国家工程实验室,天津科技大学生物工程学院,天津300457

出　　处：《微生物学通报》2020年第7期2309-2320,共12页Microbiology China

基　　金：国家重点研发计划(2018YFA0901700)。

摘　　要：AA9家族的裂解性多糖单加氧酶(lytic polysaccharide monooxygenase,LPMO)广泛存在于真菌中,由于其能作用于木质纤维素的结晶多糖,从而使其在生物转化生物质方面发挥重要的作用。本文首先综述了AA9家族LPMO的结构特点、催化机制、结构与功能之间的关系,其次阐述了AA9家族LPMO的微生物表达与调控,最后简单介绍了AA9家族LPMO在转化木质纤维素中的应用。The lytic polysaccharide monooxygenase(LPMO)of AA9 is widely distributed in fungi and plays an important role in the bioconversion of biomass because it can degrade crystalline polysaccharide of lignocellulose.The detailed information of the structural features,catalytic mechanism,structure and function and microbial expression and regulation of AA9 LPMO is summarized.Finally,the applications of AA9 LPMO in the conversion of lignocellulose are also discussed.

关 键 词：木质纤维素 生物转化 裂解性多糖单加氧酶 构效关系 微生物表达 

分 类 号：Q936[生物学—微生物学]