2014-2018年南京市HIV抗体不确定结果中梅毒感染情况分析  

Analysis of syphilis infection in the uncertain results of HIV Antibody from 2014 to 2018 in Nanjing City

作　　者：吴咏梅[1] 许文炯[1] 乔梦凯[1] 张洪英[1] WU Yong-mei;XU Wen-jiong;QIAO Meng-kai;ZHANG Hong-ying(Microbiological laboratory of Nanjing Municipal Center for Disease Control and Prevention,Nanjing Jiangsu,210003,China)

机构地区：[1]南京市疾病预防控制中心微生物检验科,江苏南京210003

出　　处：《职业与健康》2020年第11期1478-1481,共4页Occupation and Health

基　　金：江苏省卫生计生委2014-2015年度预防医学科研课题(Y2015002)。

摘　　要：目的分析南京市人类免疫缺陷病毒(HIV)抗体不确定结果人群中梅毒感染情况,为今后制定艾滋病和性病防治政策提供参考依据。方法用免疫印迹试验(WB)方法检测HIV抗体,分析2014-2018年南京市HIV抗体不确定样本的人群特征;用梅毒血清学方法快速血浆反应素环状卡片试验(RPR)和快速免疫层析检测法(RT)检测梅毒,分析不确定人群中梅毒感染的人群特征。结果4417例复检有反应人群中HIV抗体不确定人数为169例,HIV抗体不确定率为3.8%,梅毒血清学阳性率(20.7%)高于梅毒感染率(14.2%)。不同年份、性别、年龄、职业和标本来源人群HIV抗体不确定率比较,差异均有统计学意义(均P<0.05)。不同性别、标本来源HIV抗体不确定人群梅毒感染率比较,差异均有统计学意义(均P<0.05)。来自检测咨询、性病专科的HIV抗体不确定人群与HIV抗体阴性人群比较,梅毒感染情况差异有统计学意义(均P<0.05)。结论加强HIV抗体不确定结果中各类人群的梅毒筛查工作,对艾滋病性病防控工作具有重要意义。Objective To analyze syphilis infection in the population with uncertain human immunodeficiency virus(HIV)antibody results in Nanjing City,and to provide scientific basis for formulating AIDS and STD prevention and control policies in the future.Methods The WB method was used to detect HIV antibody,and analyzed the population characteristics of uncertain HIV antibody samples in 2014-2018 in Nanjing City.The syphilis serological method rapid plasma reagin ring card test(RPR)and rapid immunochromatography(RT)methods were used to detect syphilis,and analyzed the population characteristics of syphilis infection in uncertain population.Results The uncertainty rate of HIV antibody in Nanjing City was 3.8%,and the positive rate of syphilis(20.7%)serology was higher than that of syphilis infection(14.2%).There was significant difference in the uncertainty rate of HIV antibody among different years,genders,ages,occupations and sample sources(all P<0.05).There was significant difference in syphilis infection rate among people with uncertain HIV antibody from different genders and samples(both P<0.05).There was a significant difference in syphilis infection between HIV antibody uncertainty group and HIV antibody negative group(both P<0.05).Conclusion It is of great significance for the prevention and control of AIDS and venereal diseases to strengthen syphilis screen-ing among different kinds of people with uncertain results of HIV antibody.

关 键 词：人类免疫缺陷病毒 不确定结果 梅毒 流行病学 

分 类 号：R446.6[医药卫生—诊断学]