慢性阻塞性肺疾病早期诊断的方法探讨  

Early diagnosis of chronic obstructive pulmonary disease

作　　者：龙娇 葛海燕[1] 朱惠莉[1] Long Jiao;Ge Haiyan;Zhu Huili(Department of Respiratory Medicine,East China Hospital,Fudan University,Shanghai 200040,China)

机构地区：[1]复旦大学附属华东医院呼吸内科,上海200040

出　　处：《国际呼吸杂志》2020年第14期1116-1120,共5页International Journal of Respiration

摘　　要：近年来,慢性阻塞性肺疾病(COPD)的患病率、病死率以及所带来的社会负担逐年上升。然而研究发现,在COPD人群中,早期阶段的患者所占比重似乎越来越大。有部分患者肺功能检查虽然未能达到COPD诊断标准,但其实已经出现了一定程度的肺气体陷闭、气道异常病变和生活能力下降等。若能在气流受限尚未出现时,即受损肺阶段对该类人群进行识别,甚至进行早干预,应该会有利于延缓甚至阻断受损肺进一步发展为COPD,有利于降低COPD所带来的疾病负担和病死率。因此,寻找积极有效的早期诊断方法就显得尤为重要。本文将对早期COPD的特点及近年来COPD早期诊断的相关研究和新进展进行综述。Recently,the prevalence,mortality,and social burden of chronic obstructive pulmonary disease(COPD)have increased by years.And the study found that in COPD patients,the proportion of early stages seems to be increasing.Although some patients don,t meet the diagnostic criteria for COPD,they have already had a certain degree of airflow limitation,airway obstruction,and decline of daily life ability.If it could be identified or even intervened at the stage of damaged lung before the occurrence of continuous airflow limitation,which might delay or even prevent the development progression of COPD,and then it could be helpful to reduce the disease burden and mortality of COPD.Therefore,it is important to find effective methods for the diagnosis of COPD.This article will introduce the characteristics of early COPD,and review the new research progress in the early diagnosis of COPD.

关 键 词：肺疾病 慢性阻塞性 早期诊断 GOLD"0"期 联合诊断 数据整合分析 

分 类 号：R563.9[医药卫生—呼吸系统]