探讨血液透析超滤缓解重度肾病性水肿的临床效果及预后  

Exploration of the clinical effect and prognosis of hemodialysis ultrafiltration to relieve severe nephrotic edema

作　　者：赵晓琴 ZHAO Xiaoqin(Hemodialysis Room,the Central Hospital of Sanmenxia City,He’nan Sanmenxia 472000,China)

机构地区：[1]河南省三门峡市中心医院血液透析室,河南三门峡472000

出　　处：《上海医药》2020年第15期54-57,79,共5页Shanghai Medical & Pharmaceutical Journal

摘　　要：目的 :探讨与分析血液透析超滤缓解重度肾病性水肿的临床效果及预后。方法 :选择80例重度肾病性水肿患者为观察研究对象,将患者分为对照组(行常规方式治疗)和研究组(行血液透析超滤治疗)各40例,对比分析两组患者的临床疗效。结果 :研究组中血白蛋白、血肌酐、尿素氮、尿蛋白、N-乙酰基-β-D-氨基葡萄糖苷酶、尿肾脏损伤分子-1、体质量水平较对照组更低,而尿量水平、不良症状缓解率更高(P<0.05)。结论 :血液透析超滤缓解重度肾病性水肿效果显著,能够有效改善重度肾病性水肿症状和预后。Objective: To explore and analyze the clinical effect and prognosis of hemodialysis ultrafiltration on relief of severe nephrotic edema. Methods: Eighty patients with severe nephrotic edema were selected as the subjects and divided into a control group(routine treatment) and a study group(hemodialysis ultrafiltration treatment) with 40 cases each. The clinical effects were compared between the two groups and analyzed. Results: The levels of serum albumin and creatinine, urea nitrogen, urine protein, urinary N-acetyl-β-D-glucosaminidase, urinary kidney injury molecule-1 and body weight were significantly lower while the urinary volume and the remission rate of adverse symptoms were significantly higher in the study group than the control group(P<0.05). Conclusion: Hemodialysis ultrafiltration has a significant effect on relief of severe nephrotic edema and can effectively improve its symptoms and prognosis.

关 键 词：血液透析超滤 重度肾病性水肿 预后 

分 类 号：R692.9[医药卫生—泌尿科学] R459.5[医药卫生—外科学]