基于功能化氧化石墨烯用于药物载体的研究进展  

Research Progress of Drug Carriers Based on Functionalized Graphene Oxide

作　　者：胡建国 熊耀坤[1] 周立分[1] 袁恩[1] 李庆 Hu Jianguo;Xiong Yaokun;Zhou Lifen;Yuan En;Li Qing(Jiangxi University of Traditional Chinese Medicine,Jiangxi,330004)

机构地区：[1]江西中医药大学,江西330004

出　　处：《当代化工研究》2020年第15期134-135,共2页Modern Chemical Research

基　　金：江西省青年基金(20161BAB215213);江西省卫生和计划生育委员会项目(20185530);江西中医药大学科研实践班项目。

摘　　要：相对于其他药物载体,功能化氧化石墨烯因具有极大的比表面积、强的靶向性、可控释放以及良好的生物相容性和稳定性,作为药物载体越来越受到广泛的研究,尤其对氧化石墨烯两面进行功能化修饰,大大提高了其比表面积及增加了活性位点,从而达到高效载药的目的。本文主要综述了氧化石墨烯的功能化及其衍生物用于药物载体方面的最新研究进展。Compared with other drug carriers,functionalized graphene oxide has more and more extensive research as a drug carrier due to its large specific surface area,strong targeting,controlled release,and good biocompatibility and stability.Particularly,the functional modification of both sides of graphene oxide greatly improves its specific surface area and active site,so as to achieve the purpose of efficient drug loading.This article mainly reviews the latest research progress in the functionalization of graphene oxide and its derivatives for drug carriers.

关 键 词：功能化氧化石墨烯 药物载体 研究进展 

分 类 号：R943[医药卫生—药剂学]