肺鼻同治法序贯治疗对慢性持续期支气管哮喘患者肺功能和炎症因子的影响  

Efficacy of the lung and nose sequential therapy on lung function and inflammatory factors in patients with chronic persistent bronchial asthma

作　　者：贾丹[1] 唐明文[1] 余燕[1] 熊广[1] 张小瑾 陈生[1] Jia Dan

机构地区：[1]深圳市中医院,广东深圳518000

出　　处：《中医临床研究》2020年第19期108-109,共2页Clinical Journal Of Chinese Medicine

摘　　要：目的:探讨慢性持续期支气管哮喘患者采用肺鼻同治法序贯治疗对其肺功能和炎症因子的影响分析。方法:选取2017年7月-2019年2月来深圳市中医院就诊的慢性持续期支气管哮喘患者64例,随机分为观察组和对照组,各32例。对照组给予孟鲁司特钠治疗,观察组患者给予肺鼻同治法序贯治疗,比较两组患者肺功能、炎症因子水平和临床治疗效果。结果:治疗前,两组肺功能指标和血清炎症因子水平经对比无明显差异(P>0.05),治疗后,观察组用力肺活量(Forced Vital Capacity,FVC)、第一秒用力呼气量(Forced Expiratory Volume in 1 s,FEV1)和呼气峰流速(Peak Expiratory Flow,PEF)高于对照组(P<0.05),观察组白细胞介素-4(Interleukin-4,IL-4)和白细胞介素-6(Interleukin-6,IL-6)低于对照组(P<0.05),观察组临床治疗总有效率明显高于对照组(P<0.05)。结论:慢性持续期支气管哮喘患者采用肺鼻同治法序贯治疗效果显著,可明显改善患者肺功能和机体炎症因子水平,值得推广。Objective:To investigate efficacy of the lung and nose sequential therapy on lung function and inflammatory factors in patients with chronic persistent bronchial asthma.Methods:64 cases were divided into two groups,32 cases in each.The control group was given montelukast sodium,and the observation group was given the lung and nose sequential therapy.Results:After treatment,in the observation group,FVC,FEV1,and PEF were higher than the control group(P<0.05),IL-4,IL-6 were lower than those in the control group(P<0.05),and the total efficiency was significantly higher than the control group(P<0.05).Conclusion:The lung and nose sequential therapy on lung function and inflammatory factors in patients with chronic persistent bronchial asthma shows good effects,and is worthy of promotion.

关 键 词：肺鼻同治法 慢性持续期 支气管哮喘患者 肺功能 炎症因子 

分 类 号：R562.25[医药卫生—呼吸系统]