宫腔内人工授精时机对妊娠结局的影响  

Influence of intrauterine insemination timing on pregnancy outcomes

作　　者：管荷琴[1] 徐丹萍[1] GUAN Heqin;XU Danping(Taizhou Hospital, Zhejiang Province,317000)

机构地区：[1]浙江省台州医院,临海317000

出　　处：《中国计划生育学杂志》2020年第5期722-725,共4页Chinese Journal of Family Planning

基　　金：浙江省公益技术应用研究项目(2017C33217)。

摘　　要：目的:探讨宫腔内人工授精(IUI)时机对妊娠结局的影响。方法:收集本院首次行宫腔内丈夫精液人工授精(AIH)助孕的500例临床资料,根据IUI时机的不同分为排卵前组260例、排卵后组139例、排卵前+排卵后的两次组101例。对比3组妊娠结局。结果:IUI治疗后两次组生化妊娠率(22.8%)、临床妊娠率(17.8%)均高于另外两组(15.0%、15.8%,11.9%、11.5%)(P<0.05),而另外两组间无差异(P>0.05);3组流产率比较无差异(11.1%、12.5%、12.9%)(P>0.05)。3组自然周期与促排卵患者的生化妊娠率、临床妊娠率、流产率比较未见差异(P>0.05)。结论:行IUI时,选择排卵前或排卵后均能获得同等妊娠效果,但两次授精方案更有助于提高妊娠成功率。Objective:To investigate the influence of intrauterine insemination(IUI)timing on pregnancy outcomes.Methods:The data of 500 women with the first intrauterine artificial insemination of husband semen(AIH)were collected and analyzed.The women were divided into group A(260 cases were given AIH before ovulation),group B(139 cases were given AIH after ovulation),and group C(101 cases were given AIH before and after ovulation).The pregnancy outcomes were compared among the three groups.Results:After treatment,the biochemical pregnancy rate and clinical pregnancy rate of women in group C were 22.8%and 17.8%,which were significant higher than those(15.0%and 11.9%)of women in group A and those(15.8%and 11.5%)of women in group B(P<0.05),while which had no significant different between group A and B(P>0.05).There was no significant different in the abortion rate(11.1%,12.5%,and 12.9%)among the three groups(P>0.05).There were no significant difference in biochemical pregnancy rate,clinical pregnancy rate,and abortion rate between women with natural cycle and the women with ovulation induction cycle(P>0.05).There was no significant difference in biochemical pregnancy rate,clinical pregnancy rate and abortion rate of women in each group of the three groups between women with natural cycle and the women with ovulation induction cycle(P>0.05).Conclusion:AIH before ovulation and AIH after ovulation have the same clinical rate,but two times AIH before and after ovulation can improve the success rate of pregnancy.

关 键 词：宫腔内人工授精 受精时机 妊娠成功率 流产率 自然周期 促排卵周期 

分 类 号：R714.8[医药卫生—妇产科学]