高通量透析对尿毒症中医证候积分与C-反应蛋白的影响  

Effect of High Flux Dialysis on TCM Syndrome Score and C-reactive Protein in Uremic Patients

作　　者：张坤[1] 余冠华[1] 赵利 印南 王美 ZHANG Kun;YU Guanhua;ZHAO Li;YIN Nan;WANG Mei(Taihe County Hospital of Chinese Medicine,Anhui Taihe 236600,China)

机构地区：[1]安徽省阜阳市太和县中医院,安徽太和236600

出　　处：《中医药临床杂志》2020年第7期1290-1292,共3页Clinical Journal of Traditional Chinese Medicine

基　　金：2017年度市级重点专科建设项目(阜阳市卫中【2017】151号);阜阳市卫计委科研课题(阜阳市卫中【2014】483号)。

摘　　要：目的:观察高通量透析对尿毒症血液透析患者中医证候积分以及C-反应蛋白(CRP)的影响。方法:选择尿毒症血液透析患者60例,随机分为高通量透析组和低通量透析组,同时辨证所出现的中医证候;治疗后,分别观察2组患者治疗前后中医证候疗效积分及Ca、P、PTH、Alb、 HB、CRP指标的变化。结果:①治疗后,高通量透析组能降低中医证候积分,其改善中医证候总有效率高于低通量透析组(P<0.05)。两组Ca、P、 PTH、Alb、HB 较治疗前变化无统计学意义(P>0.05);高通量透析组能显著降低CRP(P<0.05),且较低通量透析组下降有显著性差异(P<0.05)。结论:高通量透析与低通量透析相比,可减少尿毒症血液透析患者中医证候积分,改善患者微炎症状态。Objective:To observe the effect of high-throughput dialysis on TCM syndrome scores and C-reactive protein (CRP) in hemodialysis patients with uremia.Methods:Sixty patients with uremic hemodialysis were selected and randomly divided into high-throughput dialysis group and low-throughput dialysis group.At the same time,TCM syndromes appeared in the syndrome differentiation;after treatment,the efficacy scores of TCM syndromes before and after treatment were observed in 2 groups And the changes of Ca,P,PTH,Alb,HB,CRP indicators.Results:① After treatment,the high-throughput dialysis group could reduce the TCM syndrome score,and the total effective rate of improving TCM syndrome was higher than that of the low-throughput dialysis group (P<0.05).The changes of Ca,P,PTH,Alb,and HB in the two groups were not statistically significant than before treatment (P>0.05);the high-throughput dialysis group could significantly reduce CRP (P<0.05),and the lower-throughput dialysis group had a significant decrease Sex difference (P<0.05).Conclusion:Compared with low-throughput dialysis,high-throughput dialysis can reduce TCM syndrome scores in patients with uremic hemodialysis and improve patients’ micro-inflammatory state.

关 键 词：高通量透析 中医证候 C-反应蛋白 

分 类 号：R459.5[医药卫生—治疗学]