氧化微晶纤维素–壳聚糖薄膜状敷料制备与表征  

Preparation and Characterization of Oxidized Microcrystalline Cellulose-Chitosan Film Dressing

作　　者：陈淑花[1] 孙婷婷 于驰[1] 许利丽 詹世平[1] 王景昌[1] 赵启成[1] Chen Shuhua;Sun Tingting;Yu Chi;Xu Lili;Zhan Shiping;Wang Jingchang;Zhao Qicheng(College of Environmental and Chemical Engineering,Dalian University,Dalian 116622,China)

机构地区：[1]大连大学环境与化学工程学院,辽宁大连116622

出　　处：《工程塑料应用》2020年第8期28-35,共8页Engineering Plastics Application

摘　　要：采用氧化微晶纤维素–壳聚糖接枝物为材料,在不同壳聚糖接枝率、铸膜液浓度以及成膜温度的条件下制备薄膜状医用敷料。利用扫描电子显微镜对膜的结构进行表征。探讨铸膜液浓度、成膜温度、接枝率对氧化微晶纤维素–壳聚糖生物膜光学性能、溶胀率、溶失率、孔隙率和力学性能的影响。结果表明,当成膜温度为50℃,接枝率为42.4%,铸膜液浓度为40 g/L时,氧化微晶纤维素–壳聚糖薄膜性能比较优异,光透过率为75.7%,溶胀率为169.09%,溶失率为10.91%,孔隙率为95.2%,拉伸强度为80.06 MPa,断裂伸长率为35.5%,其有望成为一种新型医用敷料,促进壳聚糖和氧化微晶纤维素在医用领域的发展。Using oxidized microcrystalline cellulose-chitosan graft as material,thin film medical dressing was prepared by changing chitosan grafting rate,film casting solution concentration and film-forming temperature.Scanning electron microscopy was used to characterize the structure of the film.The effects of film casting solution concentration,film forming temperature and grafting rate on the optical properties,swelling rate,dissolution rate,porosity and mechanical properties of oxidized microcrystalline cellulose-chitosan biofilms were discussed.The results show that when the film forming temperature is 50℃,the grafting rate is 42.4%,and the film casting solution is 40 g/L,its performance is excellent,the light transmittance is 75.7%,the swelling rate is 169.09%,the dissolution rate is 10.91%,and the porosity is 95.2%,the tensile strength is 80.06 MPa,and the elongation at break is 35.5%.Its excellent performance is expected to become a new medical dressing and promote the development of chitosan and oxidized microcrystalline cellulose in the medical field.

关 键 词：氧化微晶纤维素–壳聚糖接枝物 薄膜 医用敷料 

分 类 号：TB34[一般工业技术—材料科学与工程]