高强度聚焦超声治疗子宫切口妊娠的效果和安全性  

Effect and safety of high-intensity focused ultrasound in the treatment of uterine incision pregnancy

作　　者：何杰 林安平[2] 杜梅 甘晓玲[2] HE Jie;LIN An-ping;DU Mei;GAN Xiao-ling(Department of Obstetrics and Gynecology,the Second People′s Hospital of Jiulongpo District of Chongqing City,Chongqing 400000,China;Department of Obstetrics and Gynecology,the Second Affiliated Hospital of Chongqing Medical University,Chongqing 400100,China)

机构地区：[1]重庆市九龙坡区第二人民医院妇产科,重庆400000 [2]重庆医科大学附属第二医院妇产科,重庆400100

出　　处：《中国当代医药》2020年第21期122-125,共4页China Modern Medicine

摘　　要：目的探讨高强度聚焦超声(HIFU)治疗子宫切口妊娠的效果和安全性。方法选取重庆市九龙坡区第二人民医院妇产科2015年12月~2018年12月收治的130例行子宫切口妊娠术患者作为研究对象,按照随机数字表法分为对照组(65例)与观察组(65例)。对照组采用子宫动脉介入栓塞术治疗,观察组采用HIFU治疗。比较两组患者的围术期指标、β人绒毛膜促性腺激素(β-HCG)水平以及不良事件发生情况。结果观察组的血β-HCG恢复正常时间、住院天数短于对照组,阴道出血量少于对照组,差异有统计学意义(P<0.05)。治疗5 d后,观察组的血β-HCG水平低于对照组,差异有统计学意义(P<0.05)。观察组的不良事件总发生率低于对照组,差异有统计学意义(P<0.05)。结论HIFU治疗子宫切口妊娠效果显著,可缩短患者住院时间,减少阴道出血量,促进血β-HCG水平恢复,同时降低术后不良事件发生率,值得临床推广。Objective To investigate the efficacy and safety of high intensity focused ultrasound(HIFU)in the treatment of uterine incision pregnancy.Methods A total of 130 patients undergoing uterine incision pregnancy who were treated in the Department of Obstetrics and Gynecology of the Second People′s Hospital of Jiulongpo District of Chongqing City from December 2015 to December 2018 were selected as the research subjects,and they were divided into the control group(65 cases)and the observation group(65 cases)according to the random number table method.The control group was treated with uterine artery embolization,and the observation group was treated with HIFU.Perioperative indicators,β-human chorionic gonadotropin(β-HCG)levels,and adverse events were compared between the two groups of patients.Results The time to return to normalβ-HCG,the number of hospital stays in the observation group were shorter than those in the control group,and vaginal bleeding in the observation group was less than that in the control group,and the differences were statistically significant(P<0.05).After 5 days of treatment,the bloodβ-HCG level in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).The total incidence of adverse events in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion HIFU is effective in treating uterine incision pregnancy,it can shorten the length of hospital stay,reduce vaginal bleeding,promote the recovery of bloodβ-HCG levels,and reduce the incidence of postoperative adverse events,which is worthy of clinical promotion.

关 键 词：子宫切口妊娠 高强度聚焦超声 子宫动脉介入栓塞术 围术期指标 Β人绒毛膜促性腺激素 不良反应 

分 类 号：R714.2[医药卫生—妇产科学]