动脉粥样硬化斑块与中医体质相关性研究  

Correlation between Atherosclerotic Plaque and TCM Constitution

作　　者：翟超[1] 荣春书[1] 刘立明[1] 赵德喜[1] ZHAI Chao;RONG Chunshu;LIU Liming;ZHAO Dexi(Affiliated Hospital of Changchun University of Chinese Medicine,Changchun 130021,China)

机构地区：[1]长春中医药大学附属医院,长春130021

出　　处：《吉林中医药》2020年第7期910-912,共3页Jilin Journal of Chinese Medicine

基　　金：吉林省中医药管理局项目(2018069)。

摘　　要：目的探讨颈动脉粥样硬化中医体质分布特点及颈动脉斑块形成的病理机制。方法将入选的1 000例符合纳入标准的患者,行颈部动脉超声检查(颈动脉内膜—中膜厚度≥1.0 mm或有动脉粥样硬化斑块)并采集中医体质信息,以体质聚类等方法进行统计学分析,探讨颈动脉粥样硬化中医体质分类特点及不稳定颈动脉斑块形成与中医体质的相关性。结果颈动脉粥样硬化患者中出现中医体质频次分别为痰湿质(21.7%)、血瘀质(16.9%)、湿热质(15.3%)、阳虚质(14.2%)、阴虚质(9.6%)、气虚质(7.9%)、气郁质(7.4%)、特禀质(4.8%)、平和质(2.2%);中医体质类型痰湿质、血瘀质可能是影响斑块形成的主要体质类型。结论中医体质与颈动脉粥样硬化斑块的形成具有某种程度的相关性。Objective To study the distribution characteristics of TCM constitution of carotid atherosclerosis and the pathogenesis of carotid plaque formation.Methods The selected 1000 patients who met the inclusion criteria were subjected to carotid artery ultrasonography(carotid intima-medial thickness≥1.0 mm or atherosclerotic plaque)and collected TCM constitution.Statistical analysis was performed by physical clustering and other methods to explore the classification characteristics of TCM constitutions of carotid atherosclerosis and the correlation between unstable carotid plaque formation and TCM constitution.Results The frequency of TCM constitution in patients with carotid atherosclerosis are phlegm dampness(21.7%),blood stasis(16.9%),damp heat(15.3%),yang deficiency(14.2%),yin deficiency(9.6%),qi deficiency(7.9%),qi depression(7.4%),specific quality(4.8%),peace quality(2.2%).Phlegm dampness and blood stasis may be the main types of constitution that affect the formation of plaque.Conclusion There is a certain degree of correlation between TCM constitution and carotid atherosclerotic plaque formation.

关 键 词：颈动脉粥样硬化 中医体质 病理机制 

分 类 号：R259[医药卫生—中西医结合]