新生儿毒性红斑的相关危险因素及金银花、甘草、防风水剂擦涂的干预效果分析  

Related Risk Factors of Neonatal Toxic Erythema and the Intervention Effect Analysis of Honeysuckle,Liquorice root,Divaricate Saposhnikovia Root Distillate

作　　者：丁探颖 李娜[2] 封丽娟 汤明旭 孔彦君 李洋 刘亚军 DING Tanying;LI Na;FENG Lijuan;TANG Mingxu;KONG Yanjun;LI Yang;LIU Yajun(Department of Obstetrics and Gynecology,Chengde Central Hospital,Chengde 067000,Hebei Province,China;Department of Pediatrics,Chengde Central Hospital,Chengde 067000,Hebei Province,China)

机构地区：[1]承德市中心医院妇产科,河北承德067000 [2]承德市中心医院儿科,河北承德067000

出　　处：《吉林中医药》2020年第7期920-923,共4页Jilin Journal of Chinese Medicine

基　　金：承德市科学技术局项目(201801A020)。

摘　　要：目的探究新生儿毒性红斑的相关危险因素及金银花、甘草、防风水剂擦涂的干预效果。方法回顾性分析280例新生儿的临床资料,据出生后是否患有毒性红斑将其分为发生新生儿毒性红斑组(n=88)及未发生新生儿毒性红斑组(n=192),统计2组临床资料,对影响新生儿毒性红斑的相关危险因素进行多因素Logistic回归分析。将新生儿毒性红斑患儿随机分为对照组和观察组,各44例。对照组予清水沐浴常规处理,观察组在对照组基础上予金银花、甘草、防风水剂擦涂处理。2组均治疗2个疗程,每个疗程3 d。统计2组治疗后疗效、红斑消退时间及完全愈合时间。结果与未发生新生儿毒性红斑组比较,胎龄、分娩方式、产妇流产史、产妇糖尿病、新生儿Apgar评分(6~8分)是影响发生新生儿毒性红斑的危险因素(OR分别为6.250、2.123、1.753、2.203、1.731、3.563,P<0.05)。治疗后观察组的总有效率(95.45%,42/44)显著高于对照组(77.27%,34/44)(P<0.05);观察组红斑消退时间和完全愈合时间较对照组缩短(P<0.05)。结论胎龄、分娩方式、产妇流产史、产妇糖尿病、新生儿Apgar评分是新生儿毒性红斑的危险因素,针对其危险因素,可尽早进行有效的针对性措施以缓解病情并预防并发症;金银花、甘草、防风水剂擦涂可有效促进新生儿毒性红斑患儿皮肤愈合。Objective To explore the related risk factors of neonatal toxic erythema and the intervention effect of wiping on honeysuckle,liquorice and windproofing agent.Methods Retrospective analysis 280 cases of neonatal birth,according to whether suffering from toxic erythema after birth will be divided into its happening toxicity of neonatal lupus group(n=88)and no toxicity of neonatal lupus occurs group(n=192),statistics of two groups of clinical data,the related risk factors for affecting the toxicity of neonatal lupus multiariable Logistic regression analysis.88 children with neonatal toxic erythema were randomly divided into control group and observation group,each with 44 cases.The children in the control group were given the conventional treatment of bathing with clear water,and the children in the observation group were given the treatment of honeysuckle,liquorice root,divaricate saposhnikovia root distillate on the basis of the control group.Both groups were treated for 2 courses,3 days/course.The curative effect,the time of erythema regression and the time of complete healing were calculated.Results Comparison with the group without neonatal toxic erythema,Gestational age,mode of delivery,history of abortion,maternal diabetes and neonatal Apgar score(6-8 points)are the risk factors of neonatal toxic erythema(OR=6.250,2.123,1.753,2.203,1.731,3.563,P<0.05).After treatment,the total effective rate of the observation group(95.45%)(42/44)was significantly higher than that of the control group(77.27%)(34/44)(P<0.05).The time of erythema regression and complete healing in the observation group was shorter than that in the control group(P<0.05).Conclusion Gestational age,delivery mode,maternal abortion history,maternal diabetes and neonatal Apgar score are risk factors of neonatal toxic erythema,in view of its risk factors,effective and targeted measures can be taken as soon as possible to alleviate the disease and prevent complications.The application of honeysuckle,liquorice and divaricate saposhnikovia root distilla

关 键 词：新生儿毒性红斑 相关危险因素 金银花 甘草 防风 中药涂擦 

分 类 号：R272.1[医药卫生—中医儿科学]