压力-应变环对慢性肾病患者左室整体心肌做功的定量评价  

The quantitative evaluation of left ventricular global myocardial work in patients with chronic kidney disease by left ventricular pressure-strain loops

作　　者：朱慧珍 崔存英 李亚南 刘园园 黄丹青 胡彦斌 王莹 刘瑞杰 赵庆庆 刘琳 Zhu Huizhen;Cui Cunying;Li Yanan;Liu Yuanyuan;Huang Danqing;Hu Yanbin;Wang Ying;Liu Ruijie;Zhao Qingqing;Liu Lin(Department of Ultrasound,People′s Hospital of Zhengzhou University,Henan Provincial People′s Hospital,Fuwai Central China Cardiovascular Hospital,Zhengzhou 450003,China)

机构地区：[1]郑州大学人民医院,河南省人民医院阜外华中心血管病医院超声科,450003

出　　处：《中华超声影像学杂志》2020年第7期581-585,共5页Chinese Journal of Ultrasonography

基　　金：河南省医学科技攻关计划项目(2018020452)。

摘　　要：目的:应用左室压力-应变环(PSL)对慢性肾病(CKD)患者左室整体心肌做功进行定量评估。方法:选取2019年2-10月在河南省人民医院肾内科住院的CKD患者40例为病例组,根据肾小球滤过率(GFR)下降水平将CKD患者分为CKD 2~3期组、CKD 4~5期组各20例;选取同期健康志愿者20例为对照组。应用左室PSL测量左室整体心肌做功参数,包括整体做功指数(GWI)、整体有用功(GCW)、整体无用功(GWW)、整体做功效率(GWE),比较三组间各参数的差异。结果:与对照组相比,CKD 2~3期组、CKD 4~5期组GWI、GCW、GWW增高,GWE减低,差异有统计学意义(均 P<0.05)。与CKD 2~3期组相比,CKD 4~5期组GWI、GCW增高,差异有统计学意义(均 P<0.05),GWW、GWE差异无统计学意义(均 P>0.05)。 结论:左室PSL为评价CKD患者左室收缩功能的变化提供了一种新方法。Objective To quantitatively evaluate the global myocardial work of left ventricle in patients with chronic kidney disease(CKD)by left ventricular pressure-strain loops(PSL).Methods Forty patients with chronic kidney disease(CKD)in Henan Provincial People′s Hospital from February 2019 to October 2019 were chosen as case group.According to the decreased level of the glomerular filtration rate(GFR),CKD patients were divided into CKD 2-3 stage group(n=20)and CKD 4-5 stage group(n=20),and 20 healthy volunteers were selected as control group.The working parameters of the global left ventricular myocardium including the global work index(GWI),the global constructive work(GCW),the global wasted work(GWW),the global work efficiency(GWE)were measured by the left ventricular PSL,and the differences of the parameters among the three groups were compared.Results Compared with the control group,the GWI,GCW,GWW in the CKD 2-3 stage group and CKD 4-5 group were significantly higher and the GWE was lower than those in the control group differences were all(all P<0.05).Compared with the CKD 2-3 stage group,the GWI and GCW of the CKD 4-5 stage group were increased(all P<0.05),but there were no significant differences in GWW and GWE(P>0.05).Conclusions Left ventricular PSL provides a new method for evaluating the changes of left ventricular systolic function in patients with CKD.

关 键 词：超声心动描记术 慢性肾病 心肌做功 心室功能 左 

分 类 号：R692[医药卫生—泌尿科学]