骨源性外泌体微小RNA对骨代谢的影响研究进展  

Research progress on effect of microRNAs from bone-derived exosomes on bone metabolism

作　　者：郝静[1] 邓润智[1] HAO Jing;DENG Runzhi(Nanjing Stomatological Hospital,Medical School of Nanjing University,Nanjing Jiangsu 210008,China)

机构地区：[1]南京大学医学院附属口腔医院,江苏南京210008

出　　处：《转化医学杂志》2020年第4期246-248,共3页Translational Medicine Journal

基　　金：江苏省“六大人才”高峰项目(WSW-082);江苏省青年医学人才项目(QNRC2016122);南京市医学科技发展专项(YKK16161)。

摘　　要：外泌体能够参与各种体内的细胞活动,与细胞间的通讯有关.研究显示骨骼相关细胞产生的外泌体,其中含有的微小RNA能够在调节骨代谢的过程中发挥重要的作用,作者就骨源性外泌体微小RNA在骨代谢中作用的研究进展进行综述.Exosomes are involved in a variety of cellular activities in the body and are involved in cell-to-cell communication.Studies have shown that exosomes produced by bone-related cells,which contain microRNA,play an important role in regulating bone metabolism.This review summarizes the research progress in the role of microRNA from bone-derived exosomes in bone metabolism.

关 键 词：骨代谢 外泌体 微小RNA 

分 类 号：R336[医药卫生—人体生理学]