2009-2018年甘肃省脑炎脑膜炎症候群主要病原流行特征分析  

Epidemiological characteristics of major pathogens of Encephalitis meningitis syndrome,Gansu,2009-2018

作　　者：袁艳 孟蕾[2] 汪丽娟 刘新凤[2] 周建珲 蒋小娟[2] 李娟生[1] YUAN Yan;MENG Lei;WANG Li-juan;LIU Xin-feng;ZHOU Jian-hun;JIANG Xiao-juan;LI Juan-sheng(Department of Epidemiology and Biostatistics,School of Public Healthy Lanzhou University,Lanzhou,Gansu 730000,China)

机构地区：[1]兰州大学公共卫生学院流行病与卫生统计学研究所,甘肃兰州730000 [2]甘肃省疾病预防控制中心急性传染病防治所,甘肃兰州730000

出　　处：《现代预防医学》2020年第15期2828-2830,2842,共4页Modern Preventive Medicine

基　　金：国家科技重大专项(2017ZX10103006);甘肃省自然科学基金(18JR3RA040)。

摘　　要：目的了解2009-2018年甘肃省脑炎脑膜炎症候群病原谱变迁规律及主要病原的流行特征,为相关疾病防控提供参考依据。方法利用2009-2018年甘肃省脑炎脑膜炎症候群哨点监测数据,对症候群病原构成及主要病原分布特征进行描述分析。结果2009-2018年甘肃省脑炎脑膜炎症候群病原构成以病毒(93.27%)为主,包括乙脑病毒、肠道病毒、单纯疱疹病毒与腮腺炎病毒,乙脑病毒与肠道病毒构成比总体呈上升趋势(P均<0.001)。乙脑病毒感染分布集中于40岁以上(66.92%)的农民(68.46%),以陇南地区(91.80%)高发,流行于夏秋季,8月份达到检出高峰;肠道病毒感染以男性居多,好发于15岁以下(81.51%)的学生(57.98%),流行于6-9月份,其中7月份、9月份检出阳性病例较多。结论甘肃省脑炎脑膜炎症候群病原构成以病毒为主,乙脑病毒与肠道病毒构成比总体呈上升趋势,且两者流行特征存在差异,应采取针对性的措施开展相关疾病防控。Objective To reveal the pathogens spectrum change and the epidemiological characteristics of major pathogens of Encephalitis meningitis syndrome in Gansu Province during 200-2018,and to provide reference for related diseases prevention and control.Methods The sentinel surveillance data of Encephalitis meningitis syndrome from 2009 to 2018 in Gansu Province was used,the pathogens’composition and the major pathogens’distribution characteristics of the syndrome were described and analyzed.Results During 2009-2018,the pathogens of meningitis and meningitis in Gansu Province were mainly composed of viruses(93.27%),including Japanese encephalitis virus,enterovirus,herpes simplex virus and mumps virus.The proportions of Japanese encephalitis virus and enterovirus were increased between 2009 and 2018(P<0.001).Japanese encephalitis virus distribution was concentrated in farmers(68.46%)over the age of 40(66.92%),with a high incidence in Longnan area(91.80%).The epidemic occurred in summer and autumn and reached the peak of detection in August.Enterovirus infections were predominantly among male,and occurred in students(57.98%)under the age of 15(81.51%).It was prevalent from June to September,with more positive cases detected in July and September.Conclusion Viruses are the major pathogens of Encephalitis meningitis syndrome in Gansu Province.The proportions of Japanese encephalitis virus and enteroviruses are generally increased,and there are significant differences in their prevalence characteristics.Targeted measures should be taken to prevent and control the related diseases.

关 键 词：脑炎 脑膜炎 病原 流行特征 

分 类 号：R515.2[医药卫生—内科学] R181.3[医药卫生—临床医学]