几丁糖腔内注射对半月板损伤患者术后膝关节 功能影响的动态分析  

Dynamic Analysis of the Effect of Chitin Intraluminal Injection on Tibial Joint Function in Patients with Meniscus Injury

作　　者：任晓华[1] REN Xiaohua(Nanyuan Hospital of Fengtai District,Beijing 100076,China)

机构地区：[1]北京市丰台区南苑医院,北京100076

出　　处：《大医生》2020年第3期40-42,共3页Doctor

摘　　要：目的探讨几丁糖腔内注射辅助手术治疗半月板损伤及患者术后膝关节功能的变化情况。方法选取北京市丰台区南苑医院2016年9月至2019年5月接受手术治疗的膝关节半月板损伤患者78例,随机数字表法分为玻璃酸钠组与几丁糖组,各39例,分别在术后采用玻璃酸钠与几丁糖进行关节腔内注射治疗。术后每周1次,持续4周,随访3个月。比较2组术前及术后2周、1个月、3个月膝关节活动度及膝关节功能。结果术后2周、1个月、3个月2组膝关节活动度均高于术前(P<0.05),但2组间差异均无统计学意义(P>0.05)。2组术后2周、1个月、3个月Lysholm膝关节功能评分表、国际膝关节文献委员会评估表(IKDC)评分均高于术前,且术后2周、术后1个月几丁糖组高于玻璃酸钠组(P<0.05),术后3个月2组Lysholm、IKDC评分比较差异无统计学意义(P>0.05)。术后3个月2组优良率差异无统计学意义(P>0.05)。结论几丁糖与玻璃酸钠关节腔内注射对膝关节镜半月板成形术后患者均有较好的治疗效果,但几丁糖可促进患者早期膝关节功能的恢复,远期疗效方面2种方法无明显区别。Objective To investigate the effect of intraoperative chitin injection on meniscus injury and the changes of knee function in patients after operation.Methods A total of 78 patients with knee meniscus injuries who underwent surgical treatment from September 2016 to May 2019 in Nanyuan Hospital of Fengtai District in Beijing were randomLy divided into sodium hyaluronate group and chitosan group,which were given sodium hyaluronate and chitin for intra-articular injection,once a week for 4 weeks after operation,all were followed up for 3 months.The knee joint mobility and knee joint function were compared before operation and 2 weeks,1 month,and 3 months after operation in the two groups.Results At 2 weeks,1 month,and 3 months after operation,the knee joint mobility was higher in both groups than before operation(P<0.05),but there was no significant difference between the two groups(P>0.05).The Lysholm and IKDC scores of the two groups were higher than before operation at 2 weeks,1 month,and 3 months,and the chitosan group was higher than the sodium hyaluronate group at 2 weeks and 1 month after operation(P<0.05);There was no significant difference in Lysholm and IKDC scores between the two groups after 3 months(P>0.05).There was no significant difference in excellent rate between the two groups after 3 months(P>0.05).Conclusion Chitin and sodium hyaluronate intra-articular injection have a good therapeutic effect on patients after knee arthroscopy meniscusplasty,but chitin can promote the early recovery of knee function in patients.There is no significant difference in longterm efficacy between the two methods.

关 键 词：膝关节 关节镜 半月板损伤 几丁糖 玻璃酸钠 

分 类 号：R68[医药卫生—骨科学]