预防糖尿病患者的冠状动脉粥样硬化事件的治疗进展  

Therapeutic progress in prevention of coronary atherosclerosis events in patients with diabetes mellitus

作　　者：孟子毓 丛丽[1] MENG Zi-yu;CONG Li(Department of Endocrinology,Second Affiliated Hospital of Harbin Medical University,Harbin,Heilonjiang,150001,China)

机构地区：[1]哈尔滨医科大学附属第二医院内分泌科,黑龙江哈尔滨150001

出　　处：《心血管康复医学杂志》2020年第4期485-488,共4页Chinese Journal of Cardiovascular Rehabilitation Medicine

摘　　要：糖尿病(D M)预后在心血管事件发生后更差,这可能至少部分是由D M患者的促血栓形成状态引起的.因此,当代抗血栓策略,包括更有效的药物或药物组合,可能为DM患者提供比没有DM的患者更大的临床益处.本文探讨了血小板和凝血活动的机制,并分析目前关于抗血小板治疗对糖尿病患者心血管疾病一级预防的风险-效益平衡的数据,评估了不同抗血栓治疗方法在心血管疾病二级预防中的保护作用.Prognosis of diabetes mellitus(DM)is even worse after cardiovascular events,which may be par tially caused by prothrombotic state of DM patients at least.Therefore,contemporary antithr ombotic strategies,including more potent agents or drug combination,may provide more clinical benefits for DM patients than those without DM.The present article explored mechanis ms of platelet and coagulation activity,analyzed ris k-benefit balance data of current antiplatelet therapy for primary prevention of cardiovascular diseases in DM patients,and assessed protec-tive role of different antit hr ombotic treatments in secondary prevention of cardiovascular diseases.

关 键 词：糖尿病 冠心病 一级预防 二级预防 

分 类 号：R541.4[医药卫生—心血管疾病]