安徽省淮南市无偿献血12295人梅毒感染状况分析  

Screening and confirmation of TP antibody and analysis of syphilis infection status among 12295 blood donors in Huainan area

作　　者：周涛[1] 胡晓玉[2] 吴学忠 王春阳[1] 孙友岭 张慧[1] Zhou Tao;Hu Xiaoyu;Wu Xuezhong;Wang Chunyang;Sun Youling;Zhang Hui(Department of Laboratory,Huainan Blood Center,Huainan,Anhui 232000,China;Hefei Blood Center,Hefei,Anhui 230031,China;Department of Blood Transfusion,the First Affiliated Hospital of Anhui University of Science and Technology,Huainan,Anhui 232000,China)

机构地区：[1]安徽省,淮南市中心血站检验科,232000 [2]安徽省血液中心,合肥230031 [3]安徽理工大学第一附属医院输血科,淮南232000

出　　处：《中国基层医药》2020年第14期1711-1715,共5页Chinese Journal of Primary Medicine and Pharmacy

基　　金：安徽省采供血系统血站科研技术合作项目(2015AHBC02)。

摘　　要：目的了解安徽省淮南市12295人无偿献血者的梅毒感染现状,为公共卫生管理工作提供参考依据。方法收集淮南市中心血站2017年4月1日至2017年9月30日的无偿献血者12295人血标本,采用酶联免疫吸附测定法进行梅毒螺旋体(TP)抗体筛检,采用梅毒螺旋体颗粒凝集试验(TPPA)对TP抗体筛检不合格献血者标本进行梅毒确认试验。结果淮南市12295人无偿献血者中TPPA阳性48人,TPPA阳性率为3.90‰(48/12295);男性献血者TPPA阳性率3.12‰(22/7048)、女性4.96‰(26/5247),差异无统计学意义(u=1.61,P>0.05);已婚献血者TPPA阳性率5.33‰(42/7884)、未婚2.01‰(6/2989),差异有统计学意义(u=2.33,P<0.05);不同文化程度献血者TPPA阳性率差异有统计学意义(χ^2=29.94,P<0.05),而不同血型献血者TPPA阳性率差异无统计学意义(χ^2=2.24,P>0.05)。结论安徽省淮南市无偿献血者中,不同婚姻状况、不同文化程度者TPPA阳性率存在明显差异。Objective To understand the current situation of syphilis infection among 12295 blood donors in Huainan area,so as to provide reference for the management of public health.Methods The Treponema pallidum(TP)antibody of the blood donors was screened by enzyme-linked immunosorbent assay,and the unqualified blood donors for TP antibody were confirmed by Treponema pallidum particle agglutination(TPPA).Results There were 48 blood donors TPPA positive among 12295 blood donors in Huainan area,and the TPPA positive rate was 3.90‰(48/12295).There was no statistically significant difference in the TPPA positive rate of the different gender blood donors[male 3.12‰(22/7048)vs.female 4.96‰(26/5247)]in Huainan area(u=1.61,P>0.05).There was statistically significant difference in the TPPA positive rate of the different marriage blood donors[married 5.33‰(42/7884)vs.unmarried 2.01‰(6/2989)]in Huainan area(u=2.33,P<0.05).There was statistically significant difference in the TPPA positive rate of the blood donors among different education level in Huainan area(χ^2=29.94,P<0.05).There was no statistically significant difference in the TPPA positive rate of the blood donors among ABO blood groups in Huainan area(χ^2=2.24,P>0.05).Conclusion There are significant differences in the TPPA positive rates of the blood donors among marital status and education level in Huainan area.

关 键 词：梅毒血清诊断 抗体 酶联免疫吸附测定 血库 献血者 淮南 

分 类 号：R759.1[医药卫生—皮肤病学与性病学] R193.3[医药卫生—临床医学]