2009~2019年德州市流感流行特征及病原学分析  

Analysis on epidemiological characteristics and etiology of influenza,Dezhou city,2009-2019

作　　者：王国强[1] 曹静[1] 王冬梅[1] 崔永彪[1] 徐北霜[1] 董健[1] WANG Guo-qiang;CAO Jing;WANG Dong-mei;CUI Yong-biao;XU Bei-shuang;DONG Jian(Dezhou City Center for Disease Control and Prevention,Dezhou,Shandong,253016,China)

机构地区：[1]德州市疾病预防控制中心,山东德州253016

出　　处：《预防医学论坛》2020年第6期434-439,共6页Preventive Medicine Tribune

摘　　要：目的了解德州市流感流行特征和病原学监测结果,探讨其流行规律,为流感防控提供科学依据。方法对德州市2009~2019监测年度流感样病例(Influenza-like,ILI)报告数据、流感病原学检测数据以及流感聚集性疫情进行流行病学分析。结果2009~2019监测年度,德州市共报告ILI 91860例,平均ILI%为4.99%,各年度ILI%差异有统计学意义(P<0.01);ILI年龄以0~4岁组为主(51.76%),ILI和ILI%总体呈季节性变化,每年的11月至次年3月份为发病高峰。实验室共检测流感样病例标本11327份,阳性检出率为16.25%,各年龄组流感阳性检出率有显著性差异(P<0.01),男女性阳性检出率无显著性差异(P>0.05),15岁以下年龄组占阳性病例的76.64%。德州市流感流行毒株主要为甲型H1N1、H3N2,B型Yamagata系和Victoria系,每年优势株有差异,同1年存在不同亚型的交替流行。2009~2019监测年度共报告流感聚集性疫情40起,发生场所以中小学为主(占67.50%)。结论德州市流感高峰为冬春季,流感病毒亚型每年交替流行。15岁以下人群为流感的高危人群。Objective To understand the epidemiological characteristics and etiological monitoring results of influenza in Dezhou city,and to explore the epidemic pattern,so as to provide scientific evidence for prevention and control of influenza.Methods Epidemiological analysis was carried out on the reported data of influenza-like cases(ILI),influenza pathogen detection data and influenza aggregation epidemic situation in Dezhou city during 2009-2019.Results From 2009to 2019,a total of 91860ILI were reported from the sentinel hospitals in Dezhou city,with the average ILI%of 4.99%,statistical analysis results showed there was a difference in ILI%among years(P<0.01);the majority of cases were reported from age group of 0-4,accounted for 51.76%of the total ILI.ILI and ILI%showed seasonal variation,with the peak incidence from November to March of the following year.A total of 11327swab samples from ILI patients were collected and tested,with a positive rate of 16.25%,and remarkable difference exists among age groups(P<0.01).There was no significant difference between males and females(P>0.05).The age group under 15accounted for 76.64%of the positive cases.The influenza epidemic strains were mainly A(H1N1),A(H3N2),B Yamagata and B Victoria lineage virus in Dezhou city.The dominant strains were different every year,and there were alternate epidemics of different subtypes in the same year.A total of 40cluster events of influenza were reported during 2009-2019,mainlyoccurred in primary and secondary schools(67.50%).Conclusion The peak of influenza virus activities in Dezhou city is in winter and spring,and the different subtypes appear alternately every year.People under 15years old are the high-risk group for influenza.

关 键 词：流感 流行病学研究 病原学监测 

分 类 号：R511.7[医药卫生—内科学]