Regenerative Therapeutic Applications of Mechanized Lipoaspirate Derivatives  

作　　者：Shaoheng XIONG Qirui WANG Lihong QIU Jizhong YANG Chenggang YI 

机构地区：[1]Department of Plastic Surgery,Xijing Hospital,Fourth Military Medical University,No.15 Changle Western Road,Xi’an,Shaanxi,710036,China [2]Department of Plastic and Reconstructive Surgery,Shanghai Ninth People’s Hospital,Shanghai Jiao Tong University School of Medicine,639 Zhi Zao Ju Road,Shanghai,200011,China

出　　处：《Chinese Journal of Plastic and Reconstructive Surgery》2020年第2期120-127,共8页

摘　　要：Autologous adipose tissue is one of the most commonly used fillers.Plastic surgeons are increasingly using it in aesthetic or reconstructive surgery owing to its abundant source,easy availability,and minimal invasiveness.Increasing amount of evidence has shown its reparative ability rather than just filling utility due to the presence of adipose-derived stem cells(ADSCs)that exhibit multipotential differentiation and paracrine characteristics.However,traditional enzymatic isolation of ADSCs is often difficult in clinical settings,limiting its application.Recently,with the development of mechanical techniques for preparation of lipoaspirates,bioactive adipose tissue can be successfully identified and isolated.Such components with therapeutic potential might also be helpful in tissue repair and regeneration.In this article,we introduced several types of mechanized lipoaspirates derivatives(such as emulsified fat,adipose extracellular matrix(ECM),and cell-free extraction)and their applications from bench to bedside.

关 键 词：Adipose-derived stem cells emulsified fat extracellular matrix cell-free extraction 

分 类 号：R622[医药卫生—整形外科]