我院2018年药品不良反应报表汇总分析  

Adverse Drug Reaction Reports of 2018

作　　者：谢丽君 黄小红 林小燕 XIE Li-jun;HUANG Xiao-hong;LIN Xiao-yan(Zhangzhou Affiliated Hospital to Fujian Medical University,Zhangzhou 363000,China)

机构地区：[1]福建医科大学附属漳州市医院,福建漳州363000

出　　处：《海峡药学》2020年第7期219-221,共3页Strait Pharmaceutical Journal

摘　　要：目的探讨引发药品不良反应(ADR)的原因及影响因素。方法对药学部收集的2018年全院上报的ADR报告进行统计与分析。结果 1042例不良反应报告中,合格的有1009例。其中,男586例(58.08%),女423例(41.92%);新的一般的ADR报告83例(8.23%),新的严重的ADR报告2例(0.20%),已知严重的ADR报告82例(8.13%),已知一般的ADR报告842例(83.44%);给药途径中,静脉滴注引发ADR最多,为780例(77.30%),其次为口服给药113例(11.20%);抗感染药物所致ADR比例最高,为496例(49.16%),其次为抗肿瘤药物103例(10.21%);以消化系统损害448例(44.40%)最常见;报告人职业类型,医生上报900例(89.20%),护士上报127例(12.59%)。结论要注意抗感染药物的合理使用,静脉给药患者要更加监护,以减少或避免ADR的发生。OBJECTIVE To investigate the causes and influencing factors of adverse drug reaction(ADR). METHODS The ADRs in the department of pharmacy reported in our hospital in the year of 2018 were statistically analyzed.RESULTS There were 1009 qualified cases among the 1042 cases of ADR reports. Amongst all the cases,586 cases were males(58.08%) and 423 cases were females;There were 83 medium new ADR cases(8.23%),2 severe new ADR cases(0.20%) and 842 previously reported medium cases(83.44%). The highest rate of administration route leading to ADRs was intravenous infusion,where 780(777.3%) cases were reported,followed by 113 cases(11.2%) caused by oral administration.The highest incidence of ADRs resulted from anti-infective drugs,where 496 cases(49.16%) were reported,followed by 103 cases(10.21%) caused by antitumor drugs;the most frequently damaged was the digestive system,where 448 cases were reported(44.40%). The occupation types of reporters 900 cases(89.20%) from doctors,127 cases(12.59%) from nurses;CONCLUSION It is necessary to focus on the rational use of anti-infective drugs and,more attention should be paid to patients who are givenintravenous drugs to reduce or prevent ADRs to occur.

关 键 词：药品不良反应 上报情况 报告类型 影响因素 

分 类 号：R969.3[医药卫生—药理学]