基于胸腺嘧啶碱基错配的汞离子传感器研究进展  

Research Progress of Mercury Ion Sensors Based on Thymine Base Mismatch

作　　者：王久军[1] 吴亚 马博文 张兴平[1] WANG Jiu-jun;WU Ya;MA Bo-wen;ZHANG Xing-ping(College of Life Science,Yangtze University,Jingzhou 434025,China)

机构地区：[1]长江大学生命科学学院,湖北荆州434025

出　　处：《分析测试学报》2020年第6期814-820,共7页Journal of Instrumental Analysis

基　　金：湖北省教育厅科学技术研究项目(Q20181321);大学生创新项目(2018141,2019289)。

摘　　要：基于汞离子和胸腺嘧啶的质子取代反应,可形成T-Hg(Ⅱ)-T碱基错配结构,该结构可作为新型汞离子传感器的良好识别元件。相较于传统汞离子检测方法在效率与精度上的不足,以T-Hg(Ⅱ)-T碱基错配结构为识别基团的新型汞离子传感器具有一定优势。该文综述了以T-Hg(Ⅱ)-T结构为识别基团,以不同类型报告基团为基础的汞离子传感器的研究进展与趋势,从而为后续汞离子传感器的开发提供参考。A T-Hg(Ⅱ)-T structure with base mismatch was formed based on the proton-substitution reaction between mercury ions and thymine,which could be used as a good recognition component for novel mercury ion sensors.Compared with the traditional detection methods,the new mercury ion sensors with T-Hg(Ⅱ)-T mismatch structure as recognizer had some advantages in efficiency and precision.In this paper,research progress and trend of this mercury ion sensors with T-Hg(Ⅱ)-T structure as recognizer based on different types of reporter groups were summarized,thus providing a reference for the development of mercury ion sensors.

关 键 词：汞离子传感器 T-Hg(Ⅱ)-T结构 识别基团 报告基团 

分 类 号：O614.243[理学—无机化学] G353.11[理学—化学]