布地奈德联合沙丁胺醇治疗支气管哮喘急性发作的效果  

Effect of budesonide combined with salbutamol in the treatment of acute b ronchial asthma attacks

作　　者：朱家良 Zhu Jialiang(Zhanyi District People’s Hospital,Qujing Yunnan 655331)

机构地区：[1]曲靖市沾益区人民医院,云南曲靖655331

出　　处：《当代医药论丛》2020年第13期115-116,共2页

摘　　要：目的:探讨联用布地奈德和沙丁胺醇对支气管哮喘急性发作患者进行治疗的临床效果。方法:将2016年11月至2019年11月在曲靖市沾益区人民医院进行治疗的137例支气管哮喘急性发作患者随机分为甲组和乙组。使用沙丁胺醇对甲组患者进行治疗。联用布地奈德和沙丁胺醇对乙组患者进行治疗。然后,比较两组患者的呼气流速峰值、第1秒用力呼气量、用力肺活量、咳嗽症状改善的时间、胸闷气短症状改善的时间、肺部哮鸣音减弱的时间及治疗的效果。结果:治疗后,乙组患者的呼气流速峰值、第1秒用力呼气量及用力肺活量均大于甲组患者,P<0.05;乙组患者咳嗽症状改善的时间、胸闷气短症状改善的时间及肺部哮鸣音减弱的时间均短于甲组患者,P<0.05;乙组患者治疗的总有效率高于甲组患者,P<0.05。结论:联用布地奈德和沙丁胺醇对支气管哮喘急性发作患者进行治疗,可改善其肺功能。Objective:To investigate the clinical effect of combined budesonide and salbutamol in the treatment of patients with acute bronchial asthma.Methods:137 patients with acute attack of bronchial asthma who were treated in Zhanyi District People’s Hospital of Qujing city from November 2016 to November 2019 were randomly divided into group A and Group B.Patients in group A were treated with albuterol.Group B patients were treated with combination budesonide and salbutamol.Then,the peak expiratory flow rate,forced expiratory volume in the first second,forced vital capacity,time to improve cough symptoms,time to improve chest weakness,time to decrease lung wheeze,and treatment effect were compared between the two groups.Results:After treatment,the peak expiratory velocity,forced expiratory volume in the first second and forced vital capacity in group B were all greater than those in group A(P<0.05).The improvement time of cough symptom,chest stuffy symptom and lung wheeze in group B were shorter than those in group A(P<0.05).The total effective rate in group B was higher than that in group A(P<0.05).Conclusion:Combined budesonide and salbutamol may improve lung function in patients with acute bronchial asthma.

关 键 词：支气管哮喘 急性发作 布地奈德 沙丁胺醇 

分 类 号：R562[医药卫生—呼吸系统]