2017~2018年某医院病原菌的分布及耐药性分析  

Distribution and Drug Resistance of Authors’ Hospital from 2017 to 2018

作　　者：朱福娣 张晨[1] 倪穗琴[1] Zhu Fudi;Zhang Chen;Ni Suiqin(Guangzhou First People’s Hospital,Guangzhou 510080,China)

机构地区：[1]广州市第一人民医院,广东广州510080

出　　处：《广东化工》2020年第15期54-56,共3页Guangdong Chemical Industry

摘　　要：目的探究我院临床感染中革兰阳性菌及革兰阴性菌的病原菌分布及其耐药性,为指导临床合理用药提供理论依据。方法分析2017年1月至2018年12月住院和门诊病人送检的细菌培养标本,并进行药物敏感性试验。结果 11822株病原菌中,革兰阴性菌6871株(58.2%),以大肠埃希氏菌(19.2%)为主,大肠埃希氏菌对环丙沙星(56.6%)等具有较高的耐药性,对阿米卡星(1.5%)等具有较低的耐药性,未见对替加环素有产生耐药。革兰阳性菌3498株(29.6%),以凝固酶阴性葡萄球菌为主,凝固酶阴性葡萄球菌对青霉素G(91.0%)等具有较高的耐药性,对利福平(10.6%)的耐药性低,对万古霉素、替加环素、利奈唑胺均未见耐药株。真菌1438株(12.2%),主要以白色念珠菌(6.8%)为主。结论应加强对《抗菌药物临床应用指导原则》的学习和运用,合理使用抗菌药物,提高感染性疾病诊断和治疗水平。Objective To understand the distribution and drug resistance of Gram-positive and Gram-negative bacteria in clinical infection of our hospital, and to provide theoretical basis for guiding clinical rational drug use. Methods Bacterial culture samples sent by inpatients and outpatients from January 2017 to December 2018 were analyzed and drug sensitivity test was conducted. Results Among the 11822 pathogens, 6871(58.2 %) were Gram-negative, mainly Escherichia coli(19.2 %), with high resistance rate to ciprofloxacin(56.6 %), amikacin(1.5 %), and no resistance to tegacyclin. 3498 strains(29.6 %) of Gram-positive bacteria were mainly coagulase-negative Staphylococci, which had high resistance rate to penicillin G(91.0 %), rifampicin(10.6 %), vancomycin, tegacyclin and linezolid. 1438 strains(12.2 %) of Fungi were mainly Candida albicans(6.8 %). Conclusion It is necessary to strengthen the study and application of the guiding principles of clinical application of antibiotics, to use antibiotics reasonably, and to improve the diagnosis and treatment of infectious diseases.

关 键 词：病原菌 分布 耐药 分析 

分 类 号：TQ[化学工程]