对乙酰氨基酚引起儿童迟发性荨麻疹伴血管神经性水肿综合征一例  

Acetaminophen induced delayed-type urticaria and angioedema in a child

作　　者：刘俊保[1] 郝朵[1] Liu Junbao;Hao Duo(Department of Pharmacy,Erdos Central Hospital,Erdos 017000,China)

机构地区：[1]内蒙古自治区鄂尔多斯市中心医院药剂科,017000

出　　处：《中华儿科杂志》2020年第8期682-683,共2页Chinese Journal of Pediatrics

摘　　要：患儿4月龄,因"皮疹2 d,加重伴发热1 d"2019年11月就诊于鄂尔多斯市中心医院儿内科,根据入院时的临床症状、病史以及用药史,诊断为荨麻疹伴血管神经性水肿,并经实验室等检查排除其他病因后,考虑由药物对乙酰氨基酚引起,临床医师给予多种抗过敏药物(地氯雷他定、葡萄糖酸钙、维生素C),临床药师建议停用证据不足的维生素C与葡萄糖酸钙,仅用地氯雷他定抗过敏治疗,医师采纳并治疗5 d后好转出院。患儿使用对乙酰氨基酚3 d后出现荨麻疹,属于迟发性反应。A 4-month-old child with skin rash for 2 days and fever for 1 day was hospitalized in the Department of Pediatrics of Erdos Central Hospital in November 2019.According to the clinical symptoms,medical history and medication history at the time of admission,it was diagnosed as urticaria with angioneuroedema.In this case,the urticaria occurred 3 days after acetaminophen administration,which is a delayed reaction.

关 键 词：血管神经性水肿 地氯雷他定 抗过敏治疗 对乙酰氨基酚 葡萄糖酸钙 用药史 儿内科 抗过敏药物 

分 类 号：R758.24[医药卫生—皮肤病学与性病学]