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作 者:周世升 ZHOU Shi-Sheng(The First Surgery Department,People's Hospital of Xinbin Manchu Autonomous County of Fushun City in Liaoning Prowince,Fushun 113200,China)
机构地区:[1]辽宁省抚顺市新宾满族自治县人民医院外一科,辽宁抚顺113200
出 处:《中国药物经济学》2020年第6期90-92,共3页China Journal of Pharmaceutical Economics
摘 要:目的探讨联合应用微创穿刺血肿引流术及脑血康片对高血压性脑出血(HICH)患者血肿清除及日常生活能力的影响。方法选取辽宁省抚顺市新宾满族自治县人民医院2018年6月至2019年7月接收的HICH患者86例作为研究对象,根据盲抽法将其分为对照组与观察组,各43例。对照组实施微创穿刺血肿引流术,观察组在此基础上,观察组加用脑血康片,比较两组血肿清除情况、改良Barthel指数评定量表(MBI)及不良反应。结果两组术后7 d血肿残余量比较,差异无统计学意义(P>0.05);与对照组比较,观察组血肿清除完成时间较短,术后3 d血肿残余量较小,差异有统计学意义(P<0.05);术后2个月,与对照组比较,观察组MBI评分较高,差异有统计学意义(P<0.05);观察组不良反应发生率为6.98%,略高于对照组的2.33%,差异无统计学意义(P>0.05)。结论在HICH患者中联合应用微创穿刺血肿引流术及脑血康片治疗效果较好,可有效清除血肿,提高日常生活能力,利于患者康复。Objective To investigate the effects of minimally invasive puncture hematoma drainage and nimodipine on hematomas clearance and daily living ability in patients with hypertensive intracerebral hemorrhage(HICH). Methods A total of86 patients in People’s Hospital of Xinbin Manchu Autonomous County of Fushun City in Liaoning Province, with HICH were selected from June 2018 to July 2019 and were divided into a control group and an observation group according to blind sampling.The control group was treated with minimally invasive puncture hematoma drainage. On this basis, the observation group was treated with nimodipine. The hematomas clearance, improved Barthel index(MBI) and adverse reactions were compared between the 2 groups. Results There was no statistical difference in the residual amount of hematomas between the 2 groups7 days after operation(P>0.05);compared with the control group, the completion time of hematomas clearance was shorter and the residual amount of hematomas was smaller in the observation group 3 days after operation(P<0.05), and the MBI score in the observation group was higher than that in the control group at 2 months after operation, and the difference was statistically significant(P<0.05).The incidence of adverse reactions in the observation group was 6.98%, which was slightly higher than that in the control group(2.33%), but there was no significant difference(P>0.05). Conclusion The combined application of minimally invasive puncture hematoma drainage and nimodipine is effective in the treatment of HICH patients. It can effectively remove the hematomas,improve the daily life and is beneficial to the lapsing of the patient.
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