植物内生真菌生物活性成分研究进展  

Research advances of endophytic fungi bioactive components

作　　者：黄燕 曾东强[1] 唐文伟[1] 杜良伟[2] HUANG Yan;ZENG Dong-qiang;TANG Wen-wei;DU Liang-wei(Guangxi Key Laboratory of Agric-Environment and Agric-Products Safety,Agricultural College,Guangxi University;College of Chemistry and Chemical Engineering,Guangxi University,Nanning 530004,China)

机构地区：[1]广西大学农学院广西农业环境与农产品安全重点实验室 [2]广西大学化学化工学院,南宁530004

出　　处：《天然产物研究与开发》2020年第8期1419-1437,共19页Natural Product Research and Development

基　　金：国家自然科学基金(31960545,31760522)。

摘　　要：植物内生真菌是寄居植物组织内,与植物共生的真菌种类。植物内生真菌的次生代谢产物具有结构和生物活性多样性的特点,因而可为医药及农药创制提供先导结构,具有巨大的研究和开发价值。本文综述了近三年来(2017~2019年)从植物内生真菌中分离出来的具有生物活性的生物碱、聚酮、萜类、甾醇、蒽醌以及其他类化合物,并分别简要概述了其生物活性研究进展,以期为植物内生真菌活性代谢产物的研究与利用提供参考。Endophytic fungi live in the plant tissue and coexists with the plan.The secondary metabolites of plant endophytic fungi have the characteristics of structure and bioactive diversity,so they can provide a leading structure for the creation of medicine and pesticides,and have great research and development value.In this paper,the biologically active alkaloids,polyketones,terpenes,sterols,anthraquinones,and other compounds isolated from plant endophytic fungi in recent three years(2017-2019)were reviewed,and the research progress of their bioactivity was briefly summarized,in order to provide reference for the research and utilization of the bioactive metabolites of endophytic fungi.

关 键 词：植物内生真菌 次级代谢物 生物活性 

分 类 号：R284[医药卫生—中药学]