肺朗格汉斯细胞组织细胞增生症研究进展  

Research progress of pulmonary Langerhans cell histiocytosis

作　　者：左婷婷 苏青青 顾洁[1] 陈延斌[1] Zuo Tingting;Su Qinqqing;Gu Jie;Chen Yanbin(Department of Respiratory and Critical Care Medicine,the First Affiliated Hospital of Soochow University,Suzhou 215000,China)

机构地区：[1]苏州大学附属第一医院呼吸与危重症医学科,215000

出　　处：《国际呼吸杂志》2020年第15期1177-1182,共6页International Journal of Respiration

摘　　要：肺朗格汉斯细胞组织细胞增生症是一种罕见的间质性疾病,以大量朗格汉斯细胞在肺内异常增殖浸润为特征,逐渐形成结节、囊腔样改变、蜂窝肺并最终导致肺纤维化。该病主要累及20~40岁的吸烟人群,其临床表现无特异性,病因及发病机制尚未完全明确。由于本病在临床较为罕见,容易造成漏诊和/或误诊,为提高认识,现就近年来关于该病的研究进展作一综述。Pulmonary Langerhans cell histiocytosis(PLCH)is a rare interstital diseases.It is characterized by a large number of Langerhans cells proliferating and infiltrating abnormally in the lung,which gradually forms nodules,cysts,honeycombing and eventually leads to pulmonary fibrosis.It primarily affects the smokers among 20-40 years old.The clinical manifestation of PLCH is non-specific,the etiology and pathogenesis are not yet clear,which often leads to misdiagnosis.In order to improve the understanding,this article makes a review about PLCH.

关 键 词：肺 朗格汉斯细胞组织细胞增生症 S100 CD1A 高分辨率电子计算机断层扫描 戒烟 

分 类 号：R563[医药卫生—呼吸系统]