清热利湿化瘀方治疗淤胆型黄疸性肝炎湿瘀交阻证60例临床观察  

Clinical effect of heat-clearing,diuresis-promoting,and stasis-resolving prescription in treatment of cholestatic jaundice hepatitis with dampness-stasis stagnation: An analysis of 60 cases

作　　者：赵庆华 朱永钦 李艳 ZHAO Qinghua;ZHU Yongqin;LI Yan(Kaifeng Municipal Hospital of Traditional Chinese Medicine,Kaifeng 475000,Henan,China)

机构地区：[1]开封市中医院,河南开封475000

出　　处：《湖南中医杂志》2020年第7期5-7,共3页Hunan Journal of Traditional Chinese Medicine

基　　金：全国名老中医传承工作室建设项目(国中医药人教发[2011]41号);河南省开封市科技计划项目(1403085)。

摘　　要：目的:观察清热利湿化瘀方治疗淤胆型黄疸性肝炎湿瘀交阻证的临床疗效。方法:将90例淤胆型黄疸性肝炎湿瘀交阻证患者按照2∶1的比例随机分为治疗组和对照组。2组患者均给予保肝护肝、降酶及对症支持治疗。在此基础上,治疗组给予清热利湿化瘀方治疗,对照组给予熊去氧胆酸片治疗,2组均以1个月为1个疗程。观察2组患者综合疗效及治疗前后症状、体征积分与肝功能各项指标变化。结果:总有效率治疗组为96.7%(58/60),对照组为76.7%(23/30),2组比较,差异有统计学意义(P<0.05);2组患者症状、体征积分及肝功能各项指标治疗前后组内比较及治疗后组间比较,差异均有统计学意义(P<0.05)。结论:清热利湿化瘀方治疗淤胆型黄疸性肝炎湿瘀交阻证疗效显著,值得临床推广。Objective:To investigate the clinical effect of heat-clearing,diuresis-promoting,and stasis-resolving prescription in the treatment of cholestatic jaundice hepatitis with dampness-stasis stagnation.Methods:A total of 90 patients with cholestatic jaundice hepatitis with dampness-stasis stagnation were randomly divided into treatment group and control group at a ratio of 2∶1.In addition to liver-protecting,transaminase-lowering,and symptomatic/supportive treatment,the patients in the treatment group were given heat-clearing,diuresis-promoting,and stasis-resolving prescription,and those in the control group were given ursodeoxycholic acid tablets;each course of treatment was 1 month for both groups.The two groups were compared in terms of overall response and changes in the scores of symptoms and signs and live function parameters after treatment.Results:There was a significant difference in overall response rate between the treatment group and the control group[96.7%(58/60)vs 76.7%(23/30),P<0.05].Both groups had significant changes in the scores of symptoms and signs and live function parameters after treatment,and there were significant differences in the above indices between the two groups after treatment(P<0.05).Conclusion:Heat-clearing,diuresis-promoting,and stasis-resolving prescription has a marked clinical effect in the treatment of cholestatic jaundice hepatitis with dampness-stasis stagnation and thus holds promise for clinical application.

关 键 词：淤胆型黄疸性肝炎 湿瘀交阻证 中医药疗法 清热利湿化瘀方 

分 类 号：R259.126[医药卫生—中西医结合]