性别差异对超极速脉搏波速度与心血管疾病危险因子相关性的影响研究  

Study on the effect of gender difference on the correlation between ultrafast pulse wave velocity and cardiovascular disease risk factors

作　　者：戴萍 朱正球 王晗 邹冲 李宏波 刘福明 黄辉 DAI Ping;ZHU Zhengqiu;WANG Han;ZOU Chong;LI Hongbo;LIU Fuming;HUANG Hui(Department of Ultrasound,Affiliated Hospital of Nanjing University of Chinese Medicine/Jiangsu Provincial Hospital of Traditional Chinese Medicine,Nanjing,Jiangsu 210029,China;Department of Geratology,Affiliated Hospital of Nanjing University of Chinese Medicine/Jiangsu Provincial Hospital of Traditional Chinese Medicine,Nanjing,Jiangsu 210029,China;Department of Cardiology,Affiliated Hospital of Nanjing University of Chinese Medicine/Jiangsu Provincial Hospital of Traditional Chinese Medicine,Nanjing,Jiangsu 210029,China)

机构地区：[1]南京中医药大学附属医院/江苏省中医院超声医学科,南京210029 [2]南京中医药大学附属医院/江苏省中医院老年科,南京210029 [3]南京中医药大学附属医院/江苏省中医院心血管内科,南京210029

出　　处：《重庆医学》2020年第16期2642-2645,共4页Chongqing medicine

基　　金：江苏省第十六批“六大人才高峰”创新人才团队项目(TD-SWYY-069);江苏省中管局中医药科技发展计划重点项目(ZD201906);江苏省卫计划生育委员会科研课题(Y2018070);江苏省干部保健科研课题(BJ16021);江苏省中医院院级创新发展基金专项课题(Y2019CX33)。

摘　　要：目的研究性别差异对超极速脉搏波速度(ufPWV)与心血管疾病危险因子之间相关性的影响。方法选取排除心血管疾病史的176例健康体检者为研究对象,男女各88例。利用ufPWV技术检查每例研究对象颈动脉收缩起始脉搏波速度(PWV-BS)和收缩末期脉搏波速度(PWV-ES),同时记录测量其心血管疾病危险因子[年龄、BMI、收缩压、舒张压、血糖、胆固醇、三酰甘油、低密度脂蛋白(LDL)、高密度脂蛋白(HDL)],再分别将PWV-BS、PWV-ES与上述心血管疾病危险因子作相关性分析,并比较性别差异对其产生的影响。结果PWV-BS、PWV-ES在不同性别间比较,差异有统计学意义(P<0.05);PWV-ES与心血管疾病危险因子相关的因素多且相关度均明显优于PWV-BS;女性PWV-BS及PWV-ES与心血管疾病危险因子相关的因素均多于男性。结论性别差异可明显影响ufPWV测值与心血管疾病危险因子的相关性。Objective To research the effects of gender difference on the correlation between ultrafast pulse wave velocity and cardiovascular disease risk factors.Methods A total of 176 healthy subjects excluding cardiovascular disease history were selected,including 88 male and 88 female.The ufPWV technology was used to exam each subject′s carotid artery pulse wave velocity of beginning systole(PWV-BS)and pulse wave velocity of ending systole(PWV-ES).Also cardiovascular risk factors[age,BMI,systolic blood pressure,diastolic blood pressure,glucose,cholesterol,triglycerides,low density lipoprotein(LDL),high density lipoprotein(HDL)]were recorded and measured.The correlation between PWV-BS.PWV-ES and the above cardiovascular disease risk factors was analyzed,and the influence of gender difference on them was compared.Results PWV-BS and PWV-ES were significant differences between male and female(P<0.05).PWV-ES had more relevant factors with cardiovascular disease risk factors and was significantly better in their relevance than PWV-BS,PWV-BS and PWV-ES in female had more relevant factors with cardiovascular disease risk factors than male.Conclusion Gender difference has significant influence on the correlation between ufPWV and cardiovascular disease risk factors.

关 键 词：性别因素 个性 超极速脉搏波速度 危险因素 相关性 

分 类 号：R445.1[医药卫生—影像医学与核医学]