钯(Ⅱ)/TPPTS催化3-吡啶硼酸在水相中的Suzuki反应研究  

Palladium/TPPTS Catalyzed Suzuki Reaction of 3-Pyridylboronic Acid in Water

作　　者：付兴丽[1] 冯杰 Fu Xingli;Feng Jie(Guangxi Vocational&Technical Institute of Industry,Nanning,Guangxi 530001,China;Guangxi Zhuang Autonomous Region Institute of Metrology and Test,Nanning,Guangxi 530007,China)

机构地区：[1]广西工业职业技术学院教务科研处,广西南宁530001 [2]广西壮族自治区计量检测研究院,广西南宁530007

出　　处：《桂林师范高等专科学校学报》2020年第4期131-135,共5页Journal of Guilin Normal College

基　　金：2020年广西中青年教师科研基础能力提升项目“具有量值溯源性的高精度液体密度测量方法研究”(项目编号:2020KY39006)。

摘　　要：将钯(Ⅱ)-TPPTS(三苯基膦-3,3’,3"-三磺酸钠)配合物,作为一类高效的催化剂应用于水相中3-吡啶硼酸的Suzuki偶联反应。实验证明,多数溴代芳烃都能在此催化体系下通过反应得到中等至优异的偶联产物产率。目标产物可以通过简单萃取从反应体系中分离提纯,之后反应体系可以继续进行五次回收利用后仍不显著降低催化活性,展现了该金属-配合物催化体系优异的循环使用性能。An efficient catalyst system derived from palladium-TPPTS(triphenylphosphine-3,3',3"-trisulfonic acid trisodium salt)complex,has been established for the Suzuki reaction of 3-pyridylboronic acid in water.Various aryl bromides could give the desired coupling products in moderate to excellent yields.The resulting products could be separated from the reaction mixture by simple extraction,and the catalytic activity had no significant loss after five times'running of recycling.

关 键 词：SUZUKI反应 3-吡啶硼酸 TPPTS膦配体 钯 回收 

分 类 号：O62[理学—有机化学]