亚低温治疗新生儿缺氧缺血性脑病对血流动力学及神经行为的影响  

Effect of Mild Hypothermia on Hemodynamics and Neurobehavior of Neonatal Hypoxic-ischemic Encephalopathy

作　　者：王芳 WANG Fang(Pediatric Intensive Medicine,Wuwei Liangzhou Hospital,Wuwei 733000,China)

机构地区：[1]甘肃省武威市凉州医院小儿重症医学科,甘肃武威733000

出　　处：《中国医药指南》2020年第23期66-67,共2页Guide of China Medicine

摘　　要：目的探究分析亚低温治疗新生儿缺氧缺血性脑病对血流动力学及神经行为的影响。方法选取2016年1月至2019年6月我院产科接诊治疗的80例缺氧缺血性脑病新生儿作为观察对象,所有新生儿确诊后均接受亚低温进行治疗,对其病历资料和检查结果等进行回顾性分析,对比治疗前后患儿的血流动力学变化、新生儿神经行为测定评分(NBNA),评定亚低温治疗的效果。结果缺氧缺血性脑病新生儿接受了亚低温治疗后,新生儿的NBNA评分明显提高,且心率(HR)、心电图(ECG)、收缩压(SBP)、每搏量(SV)、左室射血分数(LVEF)等相关血气分析指标明显改善,差异具有统计学意义(P<0.05)。结论临床应用亚低温治疗新生儿缺氧缺血性脑病,能够优化患儿的血气分析指标,提高患儿的神经功能。Objective To explore and analyze the effect of mild hypothermia treatment of neonatal hypoxic-ischemic encephalopathy on hemodynamics and neurobehavior.Methods From January 2016 to June 2019,80 neonatal hypoxic-ischemic encephalopathy neonates were selected as observation subjects.All neonates are treated with mild hypothermia after diagnosis.A retrospective analysis of the medical records and examination results of all neonatal patients was performed.The hemodynamic changes and neonatal neurobehavioral score(NBNA)of the children before and after treatment were compared to assess the effect of mild hypothermia treatment.Results After receiving hypothermia treatment for neonates with hypoxic-ischemic encephalopathy,the NBNA scores of neonates were significantly improved,and the heart rate(HR),electrocardiogram(ECG),systolic blood pressure(SBP),stroke volume(SV),left Ventricular ejection fraction(LVEF)and other related blood gas analysis indicators were significantly improved,and the difference was statistically significant(P<0.05).Conclusion The clinical application of mild hypothermia in the treatment of neonatal hypoxic-ischemic encephalopathy can optimize the blood gas analysis indexes of the children and improve the neurological function of the children.

关 键 词：缺血缺氧性脑病 新生儿 亚低温 血流动力学 神经行为 

分 类 号：R722.1[医药卫生—儿科]